Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy

被引：231

作者：

Furuya, H

FernandezSalguero, P

Gregory, W

Taber, H

Steward, A

Gonzalez, FJ

Idle, JR

机构：

[1] MED SCH NEWCASTLE UPON TYNE,DEPT PHARMACOL SCI,PHARMACOGENET RES UNIT,NEWCASTLE TYNE NE2 4HH,TYNE & WEAR,ENGLAND

[2] NIH,NCI,MOLEC CARCINOGENESIS LAB,BETHESDA,MD 20892

[3] GENOTYPE LTD,NEWCASTLE TYNE NE2 4HE,TYNE & WEAR,ENGLAND

来源：

PHARMACOGENETICS | 1995年 / 5卷 / 06期

关键词：

genetic polymorphism; CYP2C9; warfarin; anticoagulation therapy;

D O I：

10.1097/00008571-199512000-00008

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：389 / 392

页数：4

共 11 条

[1] STEREOSELECTIVE INTERACTION BETWEEN THE R-ENANTIOMER OF WARFARIN AND CIMETIDINE [J].

CHOONARA, IA ;

CHOLERTON, S ;

HAYNES, BP ;

BRECKENRIDGE, AM ;

PARK, BK .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 21 (03) :271-277

[2] STANDARDIZED INITIAL WARFARIN TREATMENT - EVALUATION OF INITIAL TREATMENT RESPONSE AND MAINTENANCE DOSE PREDICTION BY RANDOMIZED TRIAL, AND RISK-FACTORS FOR AN EXCESSIVE WARFARIN RESPONSE [J].

DOECKE, CJ ;

COSH, DG ;

GALLUS, AS .

AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1991, 21 (03) :319-324

[3]

FREDRIKS DA, 1991, CLIN PHARMACY, V10, P923

[4]

FURIE B, 1992, NEW ENGL J MED, V326, P800

[5] PHARMACOGENETIC PHENOTYPING AND GENOTYPING - PRESENT STATUS AND FUTURE POTENTIAL [J].

GONZALEZ, FJ ;

IDLE, JR .

CLINICAL PHARMACOKINETICS, 1994, 26 (01) :59-70

[6]

KAMINSKY LS, 1993, MOL PHARMACOL, V43, P234

[7] CDNA AND AMINO-ACID-SEQUENCES OF 2 MEMBERS OF THE HUMAN P450IIC GENE SUBFAMILY [J].

KIMURA, S ;

PASTEWKA, J ;

GELBOIN, HV ;

GONZALEZ, FJ .

NUCLEIC ACIDS RESEARCH, 1987, 15 (23) :10053-10054

[8] THE EFFECT OF THE PLASMA-LEVELS OF PROTEIN-C AND PROTEIN-S ON THE PREDICTION OF WARFARIN MAINTENANCE DOSE REQUIREMENTS [J].

LUBETSKY, A ;

SELIGSOHN, U ;

EZRA, D ;

HALKIN, H .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1992, 52 (01) :42-49

[9] A GENETIC ALGORITHM TO IMPROVE A NEURAL NETWORK TO PREDICT A PATIENTS RESPONSE TO WARFARIN [J].

NARAYANAN, MN ;

LUCAS, SB .

METHODS OF INFORMATION IN MEDICINE, 1993, 32 (01) :55-58

[10] HYDROXYLATION OF WARFARIN BY HUMAN CDNA-EXPRESSED CYTOCHROME-P-450 - A ROLE FOR P-4502C9 IN THE ETIOLOGY OF (S)-WARFARIN DRUG-INTERACTIONS [J].

RETTIE, AE ;

KORZEKWA, KR ;

KUNZE, KL ;

LAWRENCE, RF ;

EDDY, AC ;

AOYAMA, T ;

GELBOIN, HV ;

GONZALEZ, FJ ;

TRAGER, WF .

CHEMICAL RESEARCH IN TOXICOLOGY, 1992, 5 (01) :54-59

← 1 2 →