THE CEPH CONSORTIUM LINKAGE MAP OF HUMAN CHROMOSOME-13

被引：14

作者：

BOWCOCK, AM

GERKEN, SC

BARNES, RI

SHIANG, R

JABS, EW

WARREN, AC

ANTONARAKIS, S

RETIEF, AE

VERGNAUD, G

LEPPERT, M

LALOUEL, JM

WHITE, RL

CAVALLISFORZA, LL

机构：

[1] CTR ETUD BOUCHET,VERT LE PETIT,FRANCE

[2] UNIV UTAH,SCH MED,DEPT HUMAN GENET,SALT LAKE CITY,UT 84132

[3] UNIV UTAH,SCH MED,HOWARD HUGHES MED INST,SALT LAKE CITY,UT 84132

[4] UNIV STELLENBOSCH,TYGERBERG 7505,SOUTH AFRICA

[5] JOHNS HOPKINS UNIV,SCH MED,DEPT PEDIAT,BALTIMORE,MD 21205

[6] JOHNS HOPKINS UNIV,SCH MED,CTR MED GENET,BALTIMORE,MD 21205

[7] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,BALTIMORE,MD 21205

[8] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI,BALTIMORE,MD 21205

来源：

GENOMICS | 1993年 / 16卷 / 02期

关键词：

D O I：

10.1006/geno.1993.1215

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158,203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM. © 1993 Academic Press. All rights reserved.

引用

页码：486 / 496

页数：11

共 74 条

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