1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) NEUROTOXICITY IN MICE IS ENHANCED BY PRETREATMENT WITH DIETHYLDITHIOCARBAMATE

被引：126

作者：

CORSINI, GU ^{[1
]}

PINTUS, S ^{[1
]}

CHIUEH, CC ^{[1
]}

WEISS, JF ^{[1
]}

KOPIN, IJ ^{[1
]}

机构：

[1] ARMED FORCES RADIOBIOL RES INST,DEPT BIOCHEM,BETHESDA,MD 20814

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1985年 / 119卷 / 1-2期

关键词：

D O I：

10.1016/0014-2999(85)90331-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：127 / 128

页数：2

共 5 条

[1] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[2]

CHIUEH CC, 1984, EUR J PHARMACOL, V100, P189, DOI 10.1016/0014-2999(84)90221-8

[3] NEUROCHEMICAL AND HISTOCHEMICAL CHARACTERIZATION OF NEUROTOXIC EFFECTS OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE ON BRAIN CATECHOLAMINE NEURONS IN THE MOUSE [J].

HALLMAN, H ;

LANGE, J ;

OLSON, L ;

STROMBERG, I ;

JONSSON, G .

JOURNAL OF NEUROCHEMISTRY, 1985, 44 (01) :117-127

[4]

HEIKKILA RE, 1976, J BIOL CHEM, V251, P2182

[5] CHRONIC PARKINSONISM IN HUMANS DUE TO A PRODUCT OF MEPERIDINE-ANALOG SYNTHESIS [J].

LANGSTON, JW ;

BALLARD, P ;

TETRUD, JW ;

IRWIN, I .

SCIENCE, 1983, 219 (4587) :979-980

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