OLFACTORY RECOGNITION - A SIMPLE MEMORY SYSTEM

被引：285

作者：

BRENNAN, P ^{[1
]}

KABA, H ^{[1
]}

KEVERNE, EB ^{[1
]}

机构：

[1] UNIV CAMBRIDGE, DEPT ANAT, CAMBRIDGE CB3 8AA, ENGLAND

来源：

SCIENCE | 1990年 / 250卷 / 4985期

关键词：

D O I：

10.1126/science.2147078

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mice have an olfactory (pheromone) recognition memory located at the first relay in the sensory system. It is acquired with one-trial learning, contingent upon norepinephrine activation at mating, and lasts for several weeks. The mechanism involves Hebbian (association-dependent) changes in synaptic efficacy at dendrodendritic synapses in the accessory olfactory bulb. As a result of this memory, males made familiar by mating are recognized by the females, thereby mitigating pregnancy block. Such a memory function is biologically important to the female, as it is required to sustain pregnancy in the presence of her stud male's odors.

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页码：1223 / 1226

页数：4

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