DOPAMINE-D2 RECEPTOR ALTERATION IN PATIENTS WITH PERIODIC MOVEMENTS IN SLEEP (NOCTURNAL MYOCLONUS)

被引：73

作者：

STAEDT, J

STOPPE, G

KOGLER, A

MUNZ, D

RIEMANN, H

EMRICH, D

RUTHER, E

机构：

[1] UNIV GOTTINGEN,DEPT PSYCHIAT,W-3400 GOTTINGEN,GERMANY

[2] UNIV GOTTINGEN,DEPT NUCL MED,W-3400 GOTTINGEN,GERMANY

来源：

JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1993年 / 93卷 / 01期

关键词：

DOPAMINE RECEPTORS; NOCTURNAL MYOCLONUS; PMS; SPET;

D O I：

10.1007/BF01244940

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Periodic movements in sleep (PMS) can cause severe sleep disturbances. We investigated the central dopamine D2 receptor density in patients with PMS with I-123-IBZM and single photon emission tomography (SPET). In PMS there was a lower I-123-I-IBZM binding in the basal ganglia compared to the control group. The results indicate a loss of central D2 receptors in PMS.

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页码：71 / 74

页数：4

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