PROBING STERIC AND HYDROPHOBIC EFFECTS ON ENZYME-SUBSTRATE INTERACTIONS BY PROTEIN ENGINEERING

被引：258

作者：

ESTELL, DA

GRAYCAR, TP

MILLER, JV

POWERS, DB

BURNIER, JP

NG, PG

WELLS, JA

机构：

[1] GENENTECH INC,DEPT BICATALYSIS,460 POINT SAN BRUNO BLVD,SAN FRANCISCO,CA 94080

[2] GENENCOR INC,DEPT RES,SAN FRANCISCO,CA 94080

[3] GENENTECH INC,DEPT DEV BIOL,SAN FRANCISCO,CA 94080

来源：

SCIENCE | 1986年 / 233卷 / 4764期

关键词：

D O I：

10.1126/science.233.4764.659

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：659 / 663

页数：5

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