PHARMACOLOGY OF SMOOTH-MUSCLE CELL REPLICATION

被引：242

作者：

JACKSON, CL ^{[1
]}

SCHWARTZ, SM ^{[1
]}

机构：

[1] UNIV WASHINGTON, SCH MED, DEPT PATHOL, SEATTLE, WA 98195 USA

来源：

HYPERTENSION | 1992年 / 20卷 / 06期

关键词：

ATHEROSCLEROSIS; GROWTH SUBSTANCES; HYPERTENSION; ESSENTIAL; MUSCLE; SMOOTH; VASCULAR;

D O I：

10.1161/01.HYP.20.6.713

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The suggestion that smooth muscle cell proliferation contributes to hypertension, atherosclerosis, and restenosis after angioplasty has led to a growing interest in the use of drugs to inhibit this process. This review summarizes pharmacological studies of smooth muscle cell proliferation in vitro and in vivo and identifies specific mediators of proliferation that are implicated by drugs binding with high affinity to enzymes or receptors.

引用

页码：713 / 736

页数：24

共 282 条

[1] EFFECTS OF CAPTOPRIL ON ATHEROSCLEROSIS IN CYNOMOLGUS MONKEYS [J].

ABERG, G ;

FERRER, P .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1990, 15 :S65-S72

[2] STABLE ANALOGS OF PROSTACYCLIN AND THROMBOXANE-A2 DISPLAY CONTRADICTORY INFLUENCES ON ATHEROSCLEROTIC PROPERTIES OF CELLS CULTURED FROM HUMAN AORTA - THE EFFECT OF CALCIUM-ANTAGONISTS [J].

AKOPOV, SE ;

OREKHOV, AN ;

TERTOV, VV ;

KHASHIMOV, KA ;

GABRIELYAN, ES ;

SMIRNOV, VN .

ATHEROSCLEROSIS, 1988, 72 (2-3) :245-248

[3]

ALBRIGHTSON CR, 1985, J IMMUNOL, V135, P1872

[4] PRESENCE OF RA AND P-SITE RECEPTORS FOR ADENOSINE COUPLED TO ADENYLATE-CYCLASE IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS [J].

ANANDSRIVASTAVA, MB ;

FRANKS, DJ ;

CANTIN, M ;

GENEST, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 108 (01) :213-219

[5] AORTIC SMOOTH-MUSCLE CELLS ARE ABLE TO CONVERT ANGIOTENSIN-I TO ANGIOTENSIN-II [J].

ANDRE, P ;

SCHOTT, C ;

NEHLIG, H ;

STOCLET, JC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1990, 173 (03) :1137-1142

[6]

ASOTRA S, 1989, TRANSPLANT P, V21, P3695

[7]

AUGUST D, 1980, SURG FORUM, V31, P337

[8] CORTICOSTEROIDS SUPPRESS CYCLOOXYGENASE MESSENGER-RNA LEVELS AND PROSTANOID SYNTHESIS IN CULTURED VASCULAR CELLS [J].

BAILEY, JM ;

MAKHEJA, AN ;

PASH, J ;

VERMA, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (03) :1159-1163

[9] THROMBIN IMMOBILIZED TO EXTRACELLULAR-MATRIX IS A POTENT MITOGEN FOR VASCULAR SMOOTH-MUSCLE CELLS - NONENZYMATIC MODE OF ACTION [J].

BARSHAVIT, R ;

BENEZRA, M ;

ELDOR, A ;

HYAM, E ;

FENTON, JW ;

WILNER, GD ;

VLODAVSKY, I .

CELL REGULATION, 1990, 1 (06) :453-463

[10] BINDING OF THROMBIN TO SUBENDOTHELIAL EXTRACELLULAR-MATRIX - PROTECTION AND EXPRESSION OF FUNCTIONAL-PROPERTIES [J].

BARSHAVIT, R ;

ELDOR, A ;

VLODAVSKY, I .

JOURNAL OF CLINICAL INVESTIGATION, 1989, 84 (04) :1096-1104

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