CRYSTALLIZATION AND PRELIMINARY-X-RAY INVESTIGATION OF RECOMBINANT HUMAN INTERLEUKIN-4

被引：12

作者：

COOK, WJ

EALICK, SE

REICHERT, P

HAMMOND, GS

LE, HV

NAGABHUSHAN, TL

TROTTA, PP

BUGG, CE

机构：

[1] UNIV ALABAMA, DEPT PHARMACOL, BIRMINGHAM, AL 35294 USA

[2] UNIV ALABAMA, DEPT BIOCHEM, BIRMINGHAM, AL 35294 USA

[3] UNIV ALABAMA, CTR MACROMOLEC CRYSTALLOG, BIRMINGHAM, AL 35294 USA

[4] SCHERING PLOUGH CORP, RES, BLOOMFIELD, NJ 07003 USA

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1991年 / 218卷 / 04期

关键词：

D O I：

10.1016/0022-2836(91)90253-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Crystals of recombinant human interleukin 4 have been grown from solutions of ammonium sulfate. The crystals are tetragonal, space-group P41212 or P43212; the unit cell axes are a = 92.2(1) A ̊ and c = 46.4(1) A ̊. The crystals are stable to X-rays for at least three days and diffract beyond 2.8 Å resolution. The crystals contain approximately 63% solvent, assuming there is one molecule in the asymmetric unit. © 1991.

引用

页码：675 / 678

页数：4

共 36 条

[1] INTERLEUKIN-4 IS A NEUTROPHIL ACTIVATOR [J].