RETINOBLASTOMA, MELANOMA AND THE ATYPICAL MOLE SYNDROME

被引：18

作者：

BATAILLE, V

HILES, R

BISHOP, JAN

机构：

[1] ROYAL LONDON HOSP, DEPT DERMATOL, ICRF, SKIN TUMOUR LAB, LONDON E1 1BB, ENGLAND

[2] FRENCHAY HOSP, BRISTOL BS16 1LE, AVON, ENGLAND

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1995年 / 132卷 / 01期

关键词：

D O I：

10.1111/j.1365-2133.1995.tb08639.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Retinoblastoma patients and their relatives appear to have an increased risk of other cancers, especially melanoma, which represents 7% of second primaries in retinoblastoma survivors. Individuals belonging to families with the atypical mole syndrome (another family cancer syndrome with a genetic susceptibility to melanoma) have a recognizable phenotype, with many atypical melanocytic naevi. We report two families in which both retinoblastoma and melanoma occurred. It is of interest that in these families atypical melanocytic naevi were also demonstrated.

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页码：134 / 138

页数：5

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