AZIDOTHYMIDINE STEADY-STATE PHARMACOKINETICS IN PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX

被引：54

作者：

LASKIN, OL

DEMIRANDA, P

BLUM, MR

机构：

[1] CORNELL UNIV,MED CTR,COLL MED,NEW YORK,NY 10021

[2] WELLCOME RES LABS,RES TRIANGLE PK,NC 27709

来源：

JOURNAL OF INFECTIOUS DISEASES | 1989年 / 159卷 / 04期

关键词：

D O I：

10.1093/infdis/159.4.745

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：745 / 747

页数：3

共 9 条

[1]

BLUM MR, 1988, AM J MED, V85, P189

[2]

DEMIRANDA P, 1986, 2 P INT C ACQ IMM SY

[3] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISCHL, MA ;

RICHMAN, DD ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

SCHOOLEY, RT ;

JACKSON, GG ;

DURACK, DT ;

KING, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :185-191

[4] PHOSPHORYLATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND SELECTIVE INTERACTION OF THE 5'-TRIPHOSPHATE WITH HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE [J].

FURMAN, PA ;

FYFE, JA ;

STCLAIR, MH ;

WEINHOLD, K ;

RIDEOUT, JL ;

FREEMAN, GA ;

LEHRMAN, SN ;

BOLOGNESI, DP ;

BRODER, S ;

MITSUYA, H ;

BARRY, DW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) :8333-8337

[5] SIMULTANEOUS QUANTIFICATION OF ZIDOVUDINE AND ITS GLUCURONIDE IN SERUM BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

GOOD, SS ;

REYNOLDS, DJ ;

DEMIRANDA, P .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 431 (01) :123-133

[6] PLASMA AND CEREBROSPINAL-FLUID PHARMACOKINETICS OF 3'-AZIDO-3'-DEOXYTHYMIDINE - A NOVEL PYRIMIDINE ANALOG WITH POTENTIAL APPLICATION FOR THE TREATMENT OF PATIENTS WITH AIDS AND RELATED DISEASES [J].

KLECKER, RW ;

COLLINS, JM ;

YARCHOAN, R ;

THOMAS, R ;

JENKINS, JF ;

BRODER, S ;

MYERS, CE .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1987, 41 (04) :407-412

[7] THE TOXICITY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

RICHMAN, DD ;

FISCHL, MA ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

HIRSCH, MS ;

JACKSON, GG ;

DURACK, DT ;

NUSINOFFLEHRMAN, S .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :192-197

[8] 3'-AZIDO-3'-DEOXYTHYMIDINE TRIPHOSPHATE AS AN INHIBITOR AND SUBSTRATE OF PURIFIED HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE [J].

STCLAIR, MH ;

RICHARDS, CA ;

SPECTOR, T ;

WEINHOLD, KJ ;

MILLER, WH ;

LANGLOIS, AJ ;

FURMAN, PA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (12) :1972-1977

[9]

1988, PHYSICIANS DESK REFE, P818

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