STRUCTURAL FEATURES REQUIRED FOR LIGAND-BINDING TO THE BETA-ADRENERGIC-RECEPTOR

被引：385

作者：

DIXON, RAF ^{[1
]}

SIGAL, IS ^{[1
]}

CANDELORE, MR ^{[1
]}

SCATTERGOOD, W ^{[1
]}

RANDS, E ^{[1
]}

STRADER, CD ^{[1
]}

机构：

[1] MERCK INST THERAPEUT RES,DEPT BIOCHEM & MOLEC BIOL,RAHWAY,NJ 07065

来源：

EMBO JOURNAL | 1987年 / 6卷 / 11期

关键词：

D O I：

10.1002/j.1460-2075.1987.tb02645.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3269 / 3275

页数：7

共 17 条

[1] CLONING OF THE GENE AND CDNA FOR MAMMALIAN BETA-ADRENERGIC-RECEPTOR AND HOMOLOGY WITH RHODOPSIN [J].

DIXON, RAF ;

KOBILKA, BK ;

STRADER, DJ ;

BENOVIC, JL ;

DOHLMAN, HG ;

FRIELLE, T ;

BOLANOWSKI, MA ;

BENNETT, CD ;

RANDS, E ;

DIEHL, RE ;

MUMFORD, RA ;

SLATER, EE ;

SIGAL, IS ;

CARON, MG ;

LEFKOWITZ, RJ ;

STRADER, CD .

NATURE, 1986, 321 (6065) :75-79

[2] LIGAND-BINDING TO THE BETA-ADRENERGIC-RECEPTOR INVOLVES ITS RHODOPSIN-LIKE CORE [J].

DIXON, RAF ;

SIGAL, IS ;

RANDS, E ;

CANDELORE, MR ;

BLAKE, AD ;

STRADER, CD .

NATURE, 1987, 326 (6108) :73-77

[3] THE OPSIN FAMILY OF PROTEINS [J].

FINDLAY, JBC ;

PAPPIN, DJC .

BIOCHEMICAL JOURNAL, 1986, 238 (03) :625-+

[4] INTRINSIC GTPASE ACTIVITY DISTINGUISHES NORMAL AND ONCOGENIC RAS-P21 MOLECULES [J].

GIBBS, JB ;

SIGAL, IS ;

POE, M ;

SCOLNICK, EM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (18) :5704-5708

[5]

Gorman C., 1985, DNA CLONING PRACTICA, V1, P143

[6]

HARGRAVE PA, 1983, TRENDS BIOL SCI, V83, P128

[7] CDNA FOR THE HUMAN BETA-2-ADRENERGIC RECEPTOR - A PROTEIN WITH MULTIPLE MEMBRANE-SPANNING DOMAINS AND ENCODED BY A GENE WHOSE CHROMOSOMAL LOCATION IS SHARED WITH THAT OF THE RECEPTOR FOR PLATELET-DERIVED GROWTH-FACTOR [J].

KOBILKA, BK ;

DIXON, RAF ;

FRIELLE, T ;

DOHLMAN, HG ;

BOLANOWSKI, MA ;

SIGAL, IS ;

YANGFENG, TL ;

FRANCKE, U ;

CARON, MG ;

LEFKOWITZ, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (01) :46-50

[8] PRIMARY STRUCTURE OF PORCINE CARDIAC MUSCARINIC ACETYLCHOLINE-RECEPTOR DEDUCED FROM THE CDNA SEQUENCE [J].

KUBO, T ;

MAEDA, A ;

SUGIMOTO, K ;

AKIBA, I ;

MIKAMI, A ;

TAKAHASHI, H ;

HAGA, T ;

HAGA, K ;

ICHIYAMA, A ;

KANGAWA, K ;

MATSUO, H ;

HIROSE, T ;

NUMA, S .

FEBS LETTERS, 1986, 209 (02) :367-372

[9] CLONING, SEQUENCING AND EXPRESSION OF COMPLEMENTARY-DNA ENCODING THE MUSCARINIC ACETYLCHOLINE-RECEPTOR [J].

KUBO, T ;

FUKUDA, K ;

MIKAMI, A ;

MAEDA, A ;

TAKAHASHI, H ;

MISHINA, M ;

HAGA, T ;

HAGA, K ;

ICHIYAMA, A ;

KANGAWA, K ;

KOJIMA, M ;

MATSUO, H ;

HIROSE, T ;

NUMA, S .

NATURE, 1986, 323 (6087) :411-416

[10] ADENYLATE CYCLASE-COUPLED BETA-ADRENERGIC RECEPTORS - STRUCTURE AND MECHANISMS OF ACTIVATION AND DESENSITIZATION [J].

LEFKOWITZ, RJ ;

STADEL, JM ;

CARON, MG .

ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :159-186

← 1 2 →