REML ESTIMATION FOR SURVIVAL MODELS WITH FRAILTY

被引：137

作者：

MCGILCHRIST, CA ^{[1
]}

机构：

[1] UNIV NEW S WALES,DEPT STAT,KENSINGTON,NSW 2033,AUSTRALIA

来源：

BIOMETRICS | 1993年 / 49卷 / 01期

关键词：

FRAILTY; MAXIMUM LIKELIHOOD; MULTIVARIATE SURVIVAL TIMES; RESIDUAL MAXIMUM LIKELIHOOD;

D O I：

10.2307/2532615

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A method of estimation for generalised mixed models is applied to the estimation of regression parameters in proportional hazards models for failure times when there are repeated observations of failure on each subject. The subject effect is incorporated into the model as a random frailty term. Best linear unbiased predictors are used as an initial step in the computation of maximum likelihood and residual maximum likelihood estimates.

引用

页码：221 / 225

页数：5

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