RIBOSOMAL HETEROGENEITY FROM CHROMATIN DIMINUTION IN ASCARIS-LUMBRICOIDES

被引：49

作者：

ETTER, A ^{[1
]}

BERNARD, V ^{[1
]}

KENZELMANN, M ^{[1
]}

TOBLER, H ^{[1
]}

MULLER, F ^{[1
]}

机构：

[1] UNIV FRIBOURG,INST ZOOL,CH-1700 FRIBOURG,SWITZERLAND

来源：

SCIENCE | 1994年 / 265卷 / 5174期

关键词：

D O I：

10.1126/science.8052853

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The genome of Ascaris lumbricoides encodes both germline- and soma-specific proteins homologous to the eukaryotic small ribosomal protein (Rp) S19. The two Ascaris homologs differ by 24 amino acid substitutions and are both components of the small ribosomal subunits. In oocytes, the germline RpS19 homolog (RpS19G) predominates. During chromatin diminution, however, the gene is eliminated from all presomatic cells, and RpS19G is replaced by the product of the somatic gene (RpS19S). Chromatin diminution in A. lumbricoides causes a change in the protein composition of ribosomes during development and represents an alternative means of gene regulation.

引用

收藏

页码：954 / 956

页数：3

相关论文

共 33 条

[1] STRUCTURE AND GENOMIC ORGANIZATION OF PRORETROVIRUS-LIKE ELEMENTS PARTIALLY ELIMINATED FROM THE SOMATIC GENOME OF ASCARIS-LUMBRICOIDES [J].

AEBY, P ;

SPICHER, A ;

DECHASTONAY, Y ;

MULLER, F ;

TOBLER, H .

EMBO JOURNAL, 1986, 5 (12) :3353-3360

[2] DROSOPHILA RIBOSOMAL-PROTEIN S19 CDNA SEQUENCE [J].

BAUMGARTNER, S ;

MARTIN, D ;

CHIQUETEHRISMANN, R .

NUCLEIC ACIDS RESEARCH, 1993, 21 (16) :3897-3897

[3] ISOLATION AND NUCLEOTIDE-SEQUENCE OF THE RIBOSOMAL-PROTEIN S16-ENCODING GENE FROM ASPERGILLUS-NIDULANS [J].

BRADSHAW, RE ;

PILLAR, TM .

GENE, 1991, 108 (01) :157-162

[4]

CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2

[5] FUNCTIONAL-ANALYSIS OF A DUPLICATED LINKED PAIR OF RIBOSOMAL-PROTEIN GENES IN SACCHAROMYCES-CEREVISIAE [J].

DONOVAN, DM ;

REMINGTON, MP ;

STEWART, DA ;

CROUSE, JC ;

MILES, DJ ;

PEARSON, NJ .

MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (11) :6097-6100

[6] ELIMINATED CHROMATIN OF ASCARIS CONTAINS A GENE THAT ENCODES A PUTATIVE RIBOSOMAL-PROTEIN [J].

ETTER, A ;

ABOUTANOS, M ;

TOBLER, H ;

MULLER, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) :1593-1596

[7] HOMOLOGOUS RIBOSOMAL-PROTEIN GENES ON THE HUMAN X-CHROMOSOME AND Y-CHROMOSOME - ESCAPE FROM X-INACTIVATION AND POSSIBLE IMPLICATIONS FOR TURNER SYNDROME [J].

FISHER, EMC ;

BEERROMERO, P ;

BROWN, LG ;

RIDLEY, A ;

MCNEIL, JA ;

LAWRENCE, JB ;

WILLARD, HF ;

BIEBER, FR ;

PAGE, DC .

CELL, 1990, 63 (06) :1205-1218

[8] THE OCCURRENCE, ROLE AND EVOLUTION OF CHROMATIN DIMINUTION IN NEMATODES [J].

GODAY, C ;

PIMPINELLI, S .

PARASITOLOGY TODAY, 1993, 9 (09) :319-322

[9] COORDINATE REGULATION OF SYNTHESIS OF EUKARYOTIC RIBOSOMAL-PROTEINS [J].

GORENSTEIN, C ;

WARNER, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (05) :1547-1551

[10] STRUCTURALLY DISTINCT, STAGE-SPECIFIC RIBOSOMES OCCUR IN PLASMODIUM [J].

GUNDERSON, JH ;

SOGIN, ML ;

WOLLETT, G ;

HOLLINGDALE, M ;

DELACRUZ, VF ;

WATERS, AP ;

MCCUTCHAN, TF .

SCIENCE, 1987, 238 (4829) :933-937

← 1 2 3 4 →