BIOMECHANICS OF THE ARTERIAL-WALL UNDER SIMULATED FLOW CONDITIONS

被引：26

作者：

BRANT, AM ^{[1
]}

SHAH, SS ^{[1
]}

RODGERS, VGJ ^{[1
]}

HOFFMEISTER, J ^{[1
]}

HERMAN, IM ^{[1
]}

KORMOS, RL ^{[1
]}

BOROVETZ, HS ^{[1
]}

机构：

[1] UNIV PITTSBURGH, SCH MED, DEPT SURG, 952 SCAIFE HALL, PITTSBURGH, PA 15261 USA

来源：

JOURNAL OF BIOMECHANICS | 1988年 / 21卷 / 02期

关键词：

BIOMECHANICS - BIOMEDICAL ENGINEERING - Hemodynamics - MATHEMATICAL MODELS;

D O I：

10.1016/0021-9290(88)90004-8

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A perfusion apparatus is employed to reproduce quantifiable pulsatile hemodynamics within freshly excised canine carotid arteries. From measurements of pulsatile intraluminal and transmural pressure and the dynamic radial motion of the vessel wall, calculations are made of the vascular incremental modulus of elasticity and hoop, axial, and radial wall stresses. The results of this investigation suggest that an increase in transmural pressure from 120/80 to 240/120 mm Hg produces a marked elevation in incremental modulus and arterial wall stress. These parameters are reduced when transmural pressure is lowered while maintaining intraluminal pressure at physiologic values.

引用

页码：107 / 113

页数：7

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