TUMOR VASCULATURE - A POTENTIAL THERAPEUTIC TARGET

被引:88
作者
BAILLIE, CT [1 ]
WINSLET, MC [1 ]
BRADLEY, NJ [1 ]
机构
[1] UNIV LONDON, ROYAL FREE HOSP & SCH MED, DEPT SURG, LONDON NW3 2QG, ENGLAND
关键词
ANGIOGENESIS; ENDOTHELIUM;
D O I
10.1038/bjc.1995.323
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targeting of vascular proliferation antigens as cancer treatments.
引用
收藏
页码:257 / 267
页数:11
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