ANTIOXIDANT FUNCTION OF RECOMBINANT HUMAN NATURAL-KILLER ENHANCING FACTOR

被引：82

作者：

SAURI, H ^{[1
]}

BUTTERFIELD, L ^{[1
]}

KIM, A ^{[1
]}

SHAU, HY ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,JONSSON COMPREHENS CANC CTR,LOS ANGELES,CA 90095

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 208卷 / 03期

关键词：

D O I：

10.1006/bbrc.1995.1428

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Natural killer enhancing factor (NKEF) is a member of a new class of highly conserved antioxidant proteins. Members of this family have been described as thiol-specific antioxidants. In this study, we show that recombinant proteins encoded by the two human NKEF genes (nkef-A and B) possess antioxidant function in the protection of protein and DNA from oxidative damage. The production of separate proteins from each of the genes encoding NKEF is an important step in the elucidation of its function. (C) 1995 Academic Press, Inc.

引用

页码：964 / 969

页数：6

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