SIMULIDIN - A BLACK FLY (SIMULIUM-VITTATUM) SALIVARY-GLAND PROTEIN WITH ANTI-THROMBIN ACTIVITY

被引：22

作者：

ABEBE, M

CUPP, MS

CHAMPAGNE, D

CUPP, EW

机构：

[1] UNIV ARIZONA, DEPT ENTOMOL, TUCSON, AZ 85721 USA

[2] UNIV ARIZONA, DEPT VET SCI, TUCSON, AZ 85721 USA

来源：

JOURNAL OF INSECT PHYSIOLOGY | 1995年 / 41卷 / 11期

基金：

美国国家卫生研究院;

关键词：

SIMULIUM VITTATUM; BLACK FLIES; SALIVARY GLANDS; THROMBIN; BLOODFEEDING;

D O I：

10.1016/0022-1910(95)00039-W

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

A protein purified from the salivary gland lysate of female Simulium vittatum was found to inhibit bovine alpha-thrombin. This protein is stable to heat, has a mass of 11,334 Da and is rich in threonine, Based on N-terminal sequencing for the first 35 amino acids, no significant sequence similarity with other proteins was detected, indicating that this salivary component may be unique in structure, Because of its source and its anti-hemostatic properties, this protein has been named simulidin.

引用

页码：1001 / 1006

页数：6

共 22 条

[1] ANTICOAGULANT ACTIVITY IN SALIVARY-GLAND EXTRACTS OF BLACK FLIES (DIPTERA, SIMULIIDAE) [J].