STRUCTURE AND ENERGETICS OF LIGAND-BINDING TO PROTEINS - ESCHERICHIA-COLI DIHYDROFOLATE REDUCTASE TRIMETHOPRIM, A DRUG-RECEPTOR SYSTEM

被引：1946

作者：

DAUBEROSGUTHORPE, P ^{[1
]}

ROBERTS, VA ^{[1
]}

OSGUTHORPE, DJ ^{[1
]}

WOLFF, J ^{[1
]}

GENEST, M ^{[1
]}

HAGLER, AT ^{[1
]}

机构：

[1] AGOURON INST,505 COAST BLVD S,LA JOLLA,CA 92037

来源：

PROTEINS-STRUCTURE FUNCTION AND GENETICS | 1988年 / 4卷 / 01期

关键词：

D O I：

10.1002/prot.340040106

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：31 / 47

页数：17

共 44 条

[1]

BAKER BR, 1970, MED CHEM 1, P196

[2] CALCULATION OF THE RELATIVE CHANGE IN BINDING FREE-ENERGY OF A PROTEIN-INHIBITOR COMPLEX [J].

BASH, PA ;

SINGH, UC ;

BROWN, FK ;

LANGRIDGE, R ;

KOLLMAN, PA .

SCIENCE, 1987, 235 (4788) :574-576

[3]

Blakley R. L., 1969, FRONT BIOL

[4] MOLECULAR MECHANICS SIMULATION OF PROTEIN LIGAND INTERACTIONS - BINDING OF THYROID-HORMONE ANALOGS TO PRE-ALBUMIN [J].

BLANEY, JM ;

WEINER, PK ;

DEARING, A ;

KOLLMAN, PA ;

JORGENSEN, EC ;

OATLEY, SJ ;

BURRIDGE, JM ;

BLAKE, CCF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (23) :6424-6434

[5]

BOLIN JT, 1982, J BIOL CHEM, V257, P13650

[6] RIBONUCLEASE-A - LEAST-SQUARES REFINEMENT OF THE STRUCTURE AT 1.45 A RESOLUTION [J].

BORKAKOTI, N ;

MOSS, DS ;

PALMER, RA .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1982, 38 (AUG) :2210-2217

[7] ACTIVE-SITE DYNAMICS IN PROTEIN MOLECULES - A STOCHASTIC BOUNDARY MOLECULAR-DYNAMICS APPROACH [J].

BROOKS, CL ;

BRUNGER, A ;

KARPLUS, M .

BIOPOLYMERS, 1985, 24 (05) :843-865

[8]

BURCHALL JJ, 1965, MOL PHARMACOL, V1, P126

[9]

DAUBEROSGUTHORP.P, UNPUB

[10]

DAUBEROSGUTHORP.P, UNPUB DERIVATION VAL

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