SINGLE DOSE SAFETY, TOLERANCE, AND PHARMACOKINETICS OF HP-029 IN HEALTHY-YOUNG MEN - A POTENTIAL ALZHEIMER AGENT

被引：34

作者：

PURI, SK

HSU, RS

HO, I

LASSMAN, HB

机构：

来源：

JOURNAL OF CLINICAL PHARMACOLOGY | 1989年 / 29卷 / 03期

关键词：

D O I：

10.1002/j.1552-4604.1989.tb03328.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：278 / 284

页数：7

共 17 条

[1] NEUROTRANSMITTER-RELATED ENZYMES AND INDEXES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES [J].

BOWEN, DM ;

SMITH, CB ;

WHITE, P ;

DAVISON, AN .

BRAIN, 1976, 99 (SEP) :459-496

[2]

CUMMINGS JL, 1983, DEMENTIA CLIN APPROA, P36

[3]

DAVIES P, 1976, LANCET, V2, P1403

[4]

DAVIS KL, 1982, AM J PSYCHIAT, V139, P1421

[5] PRELIMINARY-REPORT - INTRACRANIAL CHOLINERGIC DRUG INFUSION IN PATIENTS WITH ALZHEIMERS-DISEASE [J].

HARBAUGH, RE ;

ROBERTS, DW ;

COOMBS, DW ;

SAUNDERS, RL ;

REEDER, TM .

NEUROSURGERY, 1984, 15 (04) :514-518

[6]

MOHS RC, 1985, AM J PSYCHIAT, V142, P28

[7] ISOLATION AND THE FLUOROMETRIC, HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF TACRINE [J].

PARK, TH ;

TACHIKI, KH ;

SUMMERS, WK ;

KLING, D ;

FITTEN, J ;

PERRYMAN, K ;

SPIDELL, K ;

KLING, AS .

ANALYTICAL BIOCHEMISTRY, 1986, 159 (02) :358-362

[8]

REISINE TD, 1978, BRAIN RES, V149, P447

[9] PHYSOSTIGMINE EFFECTS IN ALZHEIMERS-DISEASE - RELATIONSHIP TO DEMENTIA SEVERITY [J].

SCHWARTZ, AS ;

KOHLSTAEDT, EV .

LIFE SCIENCES, 1986, 38 (11) :1021-1028

[10] (+/-)-9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL - A POTENTIAL ALZHEIMERS-DISEASE THERAPEUTIC OF LOW TOXICITY [J].

SHUTSKE, GM ;

PIERRAT, FA ;

CORNFELDT, ML ;

SZEWCZAK, MR ;

HUGER, FP ;

BORES, GM ;

HAROUTUNIAN, V ;

DAVIS, KL .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (07) :1278-1279

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