CROSS-VALIDATION, BOOTSTRAPPING, AND PARTIAL LEAST-SQUARES COMPARED WITH MULTIPLE-REGRESSION IN CONVENTIONAL QSAR STUDIES

被引：908

作者：

CRAMER, RD ^{[1
]}

BUNCE, JD ^{[1
]}

PATTERSON, DE ^{[1
]}

FRANK, IE ^{[1
]}

机构：

[1] JERLL INC,PALO ALTO,CA 94305

来源：

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS | 1988年 / 7卷 / 01期

关键词：

D O I：

10.1002/qsar.19880070105

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：18 / 25

页数：8

共 16 条

[1] RELATIONSHIP BETWEEN LIPOPHILIC CHARACTER AND URINARY-EXCRETION OF NITROIMIDAZOLES AND NITROTHIAZOLES IN RATS [J].

CANTELLIFORTI, G ;

GUERRA, MC ;

BARBARO, AM ;

HRELIA, P ;

BIAGI, GL ;

BOREA, PA .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :555-561

[2]

CHAMBERS JM, 1983, GRAPHICAL METHODS DA, P75

[3] 5-(ALKYLSULFONYL)SALICYLANILIDES AS POTENTIAL DENTAL ANTIPLAQUE AGENTS [J].

CLARK, MT ;

COBURN, RA ;

EVANS, RT ;

GENCO, RJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (01) :25-29

[4]

DIACONIS P, 1984, SCI AM, P116

[5]

Dunn III W., 1984, QUANT STRUCT ACT REL, V3, P131

[6] SYNTHESIS AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF ANTIALLERGIC 2-HYDROXY-N-1H-TETRAZOL-5-YLBENZAMIDES AND N-(2-HYDROXYPHENYL)-1H-TETRAZOLE-5-CARBOXAMIDES [J].

FORD, RE ;

KNOWLES, P ;

LUNT, E ;

MARSHALL, SM ;

PENROSE, AJ ;

RAMSDEN, CA ;

SUMMERS, AJH ;

WALKER, JL ;

WRIGHT, DE .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :538-549

[7]

GEISSER S, 1975, J AM STAT ASSOC, V70, P328

[8]

HANSCH C, 1986, J MED CHEM, V29, P625

[9] QUANTITATIVE-EVALUATION OF THE BETA-2-ADRENOCEPTOR INTRINSIC ACTIVITY OF N-TERT-BUTYLPHENYLETHANOLAMINES [J].

IJZERMAN, AP ;

BULTSMA, T ;

TIMMERMAN, H .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :549-554

[10]

MARTIN YC, 1978, QUANTITATIVE DRUG DE, pCH7

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