MOLECULAR AND FUNCTIONAL-ASPECTS OF PECAM-1 CD31

被引：290

作者：

DELISSER, HM

NEWMAN, PJ

ALBELDA, SM

机构：

[1] WISTAR INST ANAT & BIOL,PHILADELPHIA,PA 19104

[2] BLOOD CTR SE WISCONSIN INC,MILWAUKEE,WI 53233

[3] MED COLL WISCONSIN,DEPT CELLULAR BIOL & PHARMACOL,MILWAUKEE,WI 53226

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 10期

关键词：

D O I：

10.1016/0167-5699(94)90195-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Among vascular cell adhesion molecules, platelet-endothelial cell adhesion molecule (PECAM-1/CD31) has the distinctive feature of being expressed on several of the major cell types associated with the vascular compartment. This makes it uniquely positioned to mediate multiple and important cell-cell interactions involving platelets, leukocytes and endothelial cells. Thus, PECAM-1 may represent a potential target for new therapeutic agents directed at a variety of pathological states.

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收藏

页码：490 / 495

页数：6

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