N-METHYLNALORPHINE - DEFINITION OF N-ALLYL CONFORMATION FOR ANTAGONISM AT THE OPIATE RECEPTOR

被引：18

作者：

KOBYLECKI, RJ

LANE, AC

SMITH, CFC

WAKELIN, LPG

CRUSE, WBT

EGERT, E

KENNARD, O

机构：

[1] RECKITT & COLMAN PHARMACEUT DIV,HULL HU8 7DS,ENGLAND

[2] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 11期

关键词：

D O I：

10.1021/jm00353a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1278 / 1280

页数：3

共 26 条

[1]

ARIENS EJ, 1979, TRENDS PHARM SCI, P14

[2]

ARIENS EJ, 1971, DRUG DESIGN, V1, P194

[3] IMPORTANCE OF NITROGEN LONE ELECTRON PAIR ORIENTATION IN STEREOSPECIFIC OPIATES [J].

BELLEAU, B ;

CONWAY, T ;

AHMED, FR ;

HARDY, AD .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (08) :907-908

[4]

BERNATH G, 1967, ACTA CHIM HUNG, V51, P339

[5] OPIATE RECEPTOR - MODEL EXPLAINING STRUCTURE-ACTIVITY-RELATIONSHIPS OF OPIATE AGONISTS AND ANTAGONISTS [J].

FEINBERG, AP ;

CREESE, I ;

SNYDER, SH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (11) :4215-4219

[6]

FOSTER RS, 1967, J PHARMACOL EXP THER, V157, P185

[7]

GELDERS YG, 1979, CRYST STRUCT COMMUN, V8, P995

[8] AGONIST AND ANTAGONIST ACTIONS OF MORPHINE-LIKE DRUGS ON GUINEA-PIG ISOLATED ILEUM [J].

GYANG, EA ;

KOSTERLITZ, HW .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 27 (03) :514-+

[9] NEW EXAMPLE OF A MORPHINE-SENSITIVE NEURO-EFFECTOR JUNCTION - ADRENERGIC TRANSMISSION IN MOUSE VAS-DEFERENS [J].

HENDERSON, G ;

HUGHES, J ;

KOSTERLITZ, HW .

BRITISH JOURNAL OF PHARMACOLOGY, 1972, 46 (04) :764-766

[10] ASSESSMENT IN GUINEA-PIG ILEUM AND MOUSE VAS-DEFERENS OF BENZOMORPHANS WHICH HAVE STRONG ANTINOCICEPTIVE ACTIVITY BUT DO NOT SUBSTITUTE FOR MORPHINE IN DEPENDENT MONKEY [J].

HUTCHINSON, M ;

KOSTERLITZ, HW ;

LESLIE, FM ;

WATERFIELD, AA ;

TERENIUS, L .

BRITISH JOURNAL OF PHARMACOLOGY, 1975, 55 (04) :541-546

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