ARREST OF PRETERM LABOR AND PROLONGATION OF GESTATION WITH GLYCERYL TRINITRATE, A NITRIC-OXIDE DONOR

被引：173

作者：

LEES, C

CAMPBELL, S

JAUNIAUX, E

BROWN, R

RAMSAY, B

GIBB, D

MONCADA, S

MARTIN, JF

机构：

[1] UNIV LONDON KINGS COLL HOSP,SCH MED & DENT,DEPT OBSTET & GYNAECOL,LONDON SE5 8RX,ENGLAND

[2] UNIV LONDON KINGS COLL HOSP,SCH MED & DENT,DEPT MED,LONDON SE5 8RX,ENGLAND

[3] WELLCOME RES LABS,BECKENHAM BR3 3BS,KENT,ENGLAND

来源：

LANCET | 1994年 / 343卷 / 8909期

关键词：

D O I：

10.1016/S0140-6736(94)92468-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

13 women admitted consecutively in preterm labour were recruited to an observational study of the effect of glyceryl trinitrate (GTN) patches on uterine contractions and prolongation of pregnancy. All twenty episodes of preterm labour (at 23-33 weeks' gestation) responded. 1 patient delivered because of cervical incompetence despite cessation of uterine contractions. The mean prolongation of pregnancy was 34 days. 8 babies have been born so far, and are progressing well. GTN patches appear to be a safe, well-tolerated, and non-invasive method of suppressing uterine contractions in preterm labour.

引用

页码：1325 / 1326

页数：2

共 10 条

[1] RANDOMIZED TRIAL OF ORAL INDOMETHACIN AND TERBUTALINE SULFATE FOR THE LONG-TERM SUPPRESSION OF PRETERM LABOR [J].