EFFECTS OF MESODERMAL TISSUES ON AVIAN NEURAL CREST CELL-MIGRATION

被引:107
作者
BRONNERFRASER, M [1 ]
STERN, C [1 ]
机构
[1] DEPT HUMAN ANAT,OXFORD OX1 3QX,ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1016/0012-1606(91)90071-A
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We have used microsurgical techniques to investigate the effects of embryonic mesodermal tissues on the pattern of chick neural crest cell migration in the trunk. Segmental plate or lateral plate mesenchyme was transplanted into regions encountered by neural crest cells. We found that neural crest cells are able to migrate through lateral plate mesenchyme but not through segmental plate tissue until this tissue differentiates into a sclerotome. After this stage, segmental migration is controlled by the subdivision of the sclerotome into a rostral and a caudal half: when the rostrocaudal orientation of the sclerotomes is reversed by rotating the segmental plate 180° about its rostrocaudal axis, neural crest cells migrate through the portion of the sclerotome that was originally rostral. © 1991.
引用
收藏
页码:213 / 217
页数:5
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