PEPTIDE-SYNTHESIS .8. A SYSTEM FOR SOLID-PHASE SYNTHESIS UNDER LOW-PRESSURE CONTINUOUS-FLOW CONDITIONS

被引：191

作者：

DRYLAND, A ^{[1
]}

SHEPPARD, RC ^{[1
]}

机构：

[1] MRC,MOLEC BIOL LAB,HILLS RD,CAMBRIDGE CB1 4SN,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1986年 / 01期

关键词：

D O I：

10.1039/p19860000125

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：125 / 137

页数：13

共 36 条

[1] PEPTIDE-SYNTHESIS .1. PREPARATION AND USE OF POLAR SUPPORTS BASED ON POLY(DIMETHYLACRYLAMIDE) [J].

ARSHADY, R ;

ATHERTON, E ;

CLIVE, DLJ ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (02) :529-537

[2] PEPTIDE-SYNTHESIS .3. COMPARATIVE SOLID-PHASE SYNTHESES OF HUMAN BETA-ENDORPHIN ON POLYAMIDE SUPPORTS USING TERT-BUTOXYCARBONYL AND FLUORENYLMETHOXYCARBONYL PROTECTING GROUPS [J].

ATHERTON, E ;

CAVIEZEL, M ;

FOX, H ;

HARKISS, D ;

OVER, H ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1983, (01) :65-73

[3] SYNTHESIS OF A 21-RESIDUE FRAGMENT OF HUMAN PROINSULIN BY THE POLYAMIDE SOLID-PHASE METHOD [J].

ATHERTON, E ;

HUBSCHER, W ;

SHEPPARD, RC ;

WOOLLEY, V .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1981, 362 (07) :833-839

[4] PEPTIDE-SYNTHESIS .6. PROTECTION OF THE SULFHYDRYL-GROUP OF CYSTEINE IN SOLID-PHASE SYNTHESIS USING N-ALPHA-FLUORENYLMETHOXYCARBONYLAMINO ACIDS - LINEAR OXYTOCIN DERIVATIVES [J].

ATHERTON, E ;

PINORI, M ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1985, (10) :2057-2064

[5] PEPTIDE-SYNTHESIS .2. PROCEDURES FOR SOLID-PHASE SYNTHESIS USING N-ALPHA-FLUORENYLMETHOXYCARBONYLAMINO-ACIDS ON POLYAMIDE SUPPORTS - SYNTHESIS OF SUBSTANCE-P AND OF ACYL CARRIER PROTEIN 65-74 DECAPEPTIDE [J].

ATHERTON, E ;

LOGAN, CJ ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (02) :538-546

[6] SOLID-PHASE PEPTIDE-SYNTHESIS USING N-ALPHA-FLUORENYLMETHOXYCARBONYLAMINO ACID PENTAFLUOROPHENYL ESTERS [J].

ATHERTON, E ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1985, (03) :165-166

[7] A PHYSICALLY SUPPORTED GEL POLYMER FOR LOW-PRESSURE, CONTINUOUS-FLOW SOLID-PHASE REACTIONS - APPLICATION TO SOLID-PHASE PEPTIDE-SYNTHESIS [J].

ATHERTON, E ;

BROWN, E ;

SHEPPARD, RC ;

ROSEVEAR, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1981, (21) :1151-1152

[8] INTERNAL ASSOCIATION IN SOLID-PHASE PEPTIDE-SYNTHESIS - SYNTHESIS OF CYTOCHROME-C RESIDUES 66-104 ON POLYAMIDE SUPPORTS [J].

ATHERTON, E ;

WOOLLEY, V ;

SHEPPARD, RC .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1980, (20) :970-971

[9] SIDE-CHAIN PROTECTED N-ALPHA-FLUORENYLMETHOXYCARBONYLAMINO-ACIDS FOR SOLID-PHASE PEPTIDE-SYNTHESIS - N-ALPHA-FLUORENYLMETHOXYCARBONYL-NG-4-METHOXY-2,3,6-TRIMETHYLBENZENESULPHONYL-L-ARGININE [J].

ATHERTON, E ;

SHEPPARD, RC ;

WADE, JD .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (19) :1060-1062

[10] RACEMIZATION OF ACTIVATED, URETHANE-PROTECTED AMINO-ACIDS BY PARA-DIMETHYLAMINOPYRIDINE - SIGNIFICANCE IN SOLID-PHASE PEPTIDE-SYNTHESIS [J].

ATHERTON, E ;

BENOITON, NL ;

BROWN, E ;

SHEPPARD, RC ;

WILLIAMS, BJ .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1981, (07) :336-337

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