MONOCLONAL-ANTIBODIES AGAINST DIFFERENTIATION ANTIGENS ON HUMAN MACROPHAGES

被引：19

作者：

EMMRICH, F ^{[1
]}

ANDREESEN, R ^{[1
]}

机构：

[1] UNIV FREIBURG, MED KLIN, D-7800 FREIBURG, GERMANY

来源：

IMMUNOLOGY LETTERS | 1985年 / 9卷 / 06期

关键词：

D O I：

10.1016/0165-2478(85)90056-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human macrophages matured in vitro from blood monocytes without additional exogenous activation were used to produce monoclonal antibodies (mAb). Ten of them were selected for high avidity and the best discrimination between mature macrophages and a panel of other cells including freshly prepared monocytes, B cells, T cells, granulocytes and thrombocytes. Five mAb (MAX. 1, MAX. 2, MAX. 3, MAX. 11, MAX. 24) were found to detect macrophage differentiation antigens. One mAb (MAX. 26) detects an antigen which is shared by mature macrophages and T cells.

引用

页码：321 / 324

页数：4

共 12 条

[1] PRIMARY CULTURES OF HUMAN BLOOD-BORNE MACROPHAGES GROWN ON HYDROPHOBIC TEFLON MEMBRANES [J].