CHARACTERIZATION OF IMIDAZO[1,5-A]PYRIDINE-5-HEXANOIC ACID (CGS-13080) AS A SELECTIVE THROMBOXANE SYNTHETASE INHIBITOR USING INVITRO AND INVIVO BIOCHEMICAL-MODELS

被引：46

作者：

KU, EC

MCPHERSON, SE

SIGNOR, C

CHERTOCK, H

CASH, WD

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1983年 / 112卷 / 03期

关键词：

D O I：

10.1016/0006-291X(83)91702-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：899 / 906

页数：8

共 33 条

[1] POTENTIATION BY DAZOXIBEN, A THROMBOXANE SYNTHETASE INHIBITOR, OF PLATELET-AGGREGATION INHIBITORY ACTIVITY OF A THROMBOXANE RECEPTOR ANTAGONIST AND OF PROSTACYCLIN [J].

BERTELE, V ;

DEGAETANO, G .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1982, 85 (3-4) :331-333

[2] EFFECT OF IMIDAZOLE ON THE RECOVERY FROM BILATERAL URETERAL OBSTRUCTION IN DOGS [J].

CADNAPAPHORNCHAI, P ;

BONDAR, NP ;

MCDONALD, FD .

AMERICAN JOURNAL OF PHYSIOLOGY, 1982, 243 (06) :F532-F536

[3]

CASEY LC, 1982, J PHARMACOL EXP THER, V222, P441

[4]

COKER S J, 1982, British Journal of Pharmacology, V76, p221P

[5] ELEVATED THROMBOXANE LEVELS IN THE RAT DURING ENDOTOXIC-SHOCK - PROTECTIVE EFFECTS OF IMIDAZOLE, 13-AZAPROSTANOIC ACID, OR ESSENTIAL FATTY-ACID DEFICIENCY [J].

COOK, JA ;

WISE, WC ;

HALUSHKA, PV .

JOURNAL OF CLINICAL INVESTIGATION, 1980, 65 (01) :227-230

[6] A THROMBOXANE SYNTHETASE INHIBITOR RE-ORIENTS ENDOPEROXIDE METABOLISM IN WHOLE-BLOOD TOWARDS PROSTACYCLIN AND PROSTAGLANDIN-E2 [J].

DEFREYN, G ;

DECKMYN, H ;

VERMYLEN, J .

THROMBOSIS RESEARCH, 1982, 26 (06) :389-400

[7] ARTERIAL-WALLS ARE PROTECTED AGAINST DEPOSITION OF PLATELET THROMBI BY A SUBSTANCE (PROSTAGLANDIN-X) WHICH THEY MAKE FROM PROSTAGLANDIN ENDOPEROXIDES [J].

GRYGLEWSKI, RJ ;

BUNTING, S ;

MONCADA, S ;

FLOWER, RJ ;

VANE, JR .

PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1976, 12 (05) :685-713

[8] ISOLATION AND STRUCTURE OF 2 PROSTAGLANDIN ENDOPEROXIDES THAT CAUSE PLATELET-AGGREGATION [J].

HAMBERG, M ;

SVENSSON, J ;

WAKABAYASHI, T ;

SAMUELSSON, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (02) :345-349

[9] THROMBOXANES AND PROSTACYCLIN - POSITIVE AND NEGATIVE MODULATORS OF TUMOR-GROWTH [J].

HONN, KV ;

MEYER, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 102 (04) :1122-1129

[10]

HULLIGER L, 1967, LANCET, V1, P1304

← 1 2 3 4 →