COMPLETE SEQUENCE OF THE BITHORAX COMPLEX OF DROSOPHILA

被引：138

作者：

MARTIN, CH

MAYEDA, CA

DAVIS, CA

ERICSSON, CL

KNAFELS, JD

MATHOG, DR

CELNIKER, SE

LEWIS, EB

PALAZZOLO, MJ

机构：

[1] UNIV CALIF BERKELEY, LAWRENCE BERKELEY LAB, CTR DROSOPHILA GENOME, BERKELEY, CA 94720 USA

[2] UNIV CALIF BERKELEY, LAWRENCE BERKELEY LAB, DEPT MOLEC & CELL BIOL, BERKELEY, CA 94720 USA

[3] CALTECH, DIV BIOL, PASADENA, CA 91125 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 18期

关键词：

ULTRABITHORAX; ABDOMINAL-A; ABDOMINAL-B; GLUCOSE TRANSPORTER-LIKE; DNA ANALYSIS;

D O I：

10.1073/pnas.92.18.8398

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The bithorax complex (BX-C) of Drosophila, one of two complexes that act as master regulators of the body plan of the fly, is included within a sequence of 338,234 bp (SEQ89E). This paper presents the strategy used in sequencing SEQ89E acid an analysis of its open reading frames. The BX-C sequence (BXCALL) contains 314,895 bp obtained by deletion of putative genes that are located at each end of SEQ89E and appear to be functionally unrelated to the BX-C, Only 1.4% of BXCALL codes for the three homeodomain-containing proteins of the complex. Principal findings include a putative ABD-A protein (ABD-AII) larger than a previously known ABD-A protein and a putative glucose transporter-like gene (1521 bp) located at or near the bithoraxoid (bxd), infra-abdominal-2 (iab-2) boundary on the opposite strand relative to that of the homeobox-containing genes.

引用

页码：8398 / 8402

页数：5

共 53 条

[1] FUNCTION AND EXPRESSION OF ULTRABITHORAX IN THE DROSOPHILA EMBRYO [J].