LOOKING INTO THE GROOVES OF DNA

被引：39

作者：

BOUTONNET, N

HUI, XW

ZAKRZEWSKA, K

机构：

[1] Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique, Paris, 75005, rue Pierre et Marie Curie

来源：

BIOPOLYMERS | 1993年 / 33卷 / 03期

关键词：

D O I：

10.1002/bip.360330314

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present study is aimed at understanding the effects of DNA sequence, local conformation, and curvature on groove geometry. Energy-optimized structures are obtained by Jumna methodology; groove geometry is analyzed by a recently developed technique that allows an accurate and continuous measurement of width and depth. The mechanics of groove deformations is also studied and analyzed in terms of helicoidal parameters.

引用

页码：479 / 490

页数：12

共 24 条

[1] POLY(DA).POLY(DT) IS A B-TYPE DOUBLE HELIX WITH A DISTINCTIVELY NARROW MINOR GROOVE [J].

ALEXEEV, DG ;

LIPANOV, AA ;

SKURATOVSKII, IY .

NATURE, 1987, 325 (6107) :821-823

[2] H-1 TWO-DIMENSIONAL NUCLEAR OVERHAUSER EFFECT AND RELAXATION STUDIES OF POLY(DA).POLY(DT) [J].

BEHLING, RW ;

KEARNS, DR .

BIOCHEMISTRY, 1986, 25 (11) :3335-3346

[3] LOCAL VARIABILITY AND BASE SEQUENCE EFFECTS IN DNA CRYSTAL-STRUCTURES [J].

BHATTACHARYYA, D ;

BANSAL, M .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1990, 8 (03) :539-572

[4] CONFORMATIONAL STUDIES OF D-(AAAAATTTTT)2 USING CONSTRAINTS FROM NUCLEAR OVERHAUSER EFFECTS AND FROM QUANTITATIVE-ANALYSIS OF THE CROSS-PEAK FINE-STRUCTURES IN TWO-DIMENSIONAL H-1 NUCLEAR MAGNETIC-RESONANCE SPECTRA [J].

CELDA, B ;

WIDMER, H ;

LEUPIN, W ;

CHAZIN, WJ ;

DENNY, WA ;

WUTHRICH, K .

BIOCHEMISTRY, 1989, 28 (04) :1462-1471

[5] KINKY HELIX [J].

CRICK, FHC ;

KLUG, A .

NATURE, 1975, 255 (5509) :530-533

[6] CRYSTAL-LATTICE PACKING IS IMPORTANT IN DETERMINING THE BEND OF A DNA DODECAMER CONTAINING AN ADENINE TRACT [J].

DIGABRIELE, AD ;

SANDERSON, MR ;

STEITZ, TA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (06) :1816-1820

[7] STRUCTURE OF A B-DNA DODECAMER .3. GEOMETRY OF HYDRATION [J].

DREW, HR ;

DICKERSON, RE .

JOURNAL OF MOLECULAR BIOLOGY, 1981, 151 (03) :535-556

[8]

FRATINI AV, 1982, J BIOL CHEM, V257, P14687

[9] KINKED DNA IN CRYSTALLINE COMPLEX WITH ECORI ENDONUCLEASE [J].

FREDERICK, CA ;

GRABLE, J ;

MELIA, M ;

SAMUDZI, C ;

JENJACOBSON, L ;

WANG, BC ;

GREENE, P ;

BOYER, HW ;

ROSENBERG, JM .

NATURE, 1984, 309 (5966) :327-331

[10] 3-CENTER HYDROGEN-BONDS IN DNA - MOLECULAR-DYNAMICS OF POLY(DA).POLY(DT) [J].

FRITSCH, V ;

WESTHOF, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (22) :8271-8277

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