BIOSYNTHESIS OF ARTEMISINIC ACID IN ARTEMISIA-ANNUA

被引：36

作者：

AKHILA, A

RANI, K

THAKUR, RS

机构：

[1] Central Institute of Medicinal and Aromatic Plants, Lucknow

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 07期

关键词：

Artemisia annua; artemisinic acid; biosynthesis; Compositae; monoterpenes;

D O I：

10.1016/0031-9422(90)83020-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isotopic and atomic 14C/3H ratios in artemisinic acid biosynthesized in Artemisia annua from [2- 14C, 2-3H2]-, [2-14C,4R-3H1]-, [2-14C,5-3H1]MVA have revealed that two specific 1,2-hydrogen shifts take place during the formation of the cadinane skeleton of artemisinic acid and that the gem-methyls derived from DMAPP retain their identity during the formation of this compound. © 1990.

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页码：2129 / 2132

页数：4

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