SYNTHESIS OF 6-SUBSTITUTED PYRIMIDINES BY WITTIG REACTION .I. VIA 2-AMINO-4-HYDROXY-5-PHENYLBUTYLPYRIMIDINE-6-CARBOXALDEHYDE

被引：8

作者：

BAKER, BR

JORDAAN, JH

机构：

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1966年 / 3卷 / 03期

关键词：

D O I：

10.1002/jhet.5570030315

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：315 / &

共 24 条

[1] ANALOGS OF TETRAHYDROFOLIC ACID .10. SYNTHETIC + ENZYMIC STUDIES ON CONTRIBUTION OF P-AMINOBENZOYL-L-GLUTAMATE MOIETY OF PYRIMIDYL ANALOGS TO BINDING TO SOME FOLIC COFACTOR AREA ENZYMES [J].

BAKER, BR ;

SANTI, DV ;

ALMAULA, PI ;

WERKHEISER, WC .

JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (01) :24-&

[2] ANALOGS OF TETRAHYDROFOLIC ACID .8. SYNTHESIS OF N-[1-(2-AMINO-4-MERCAPTO-6-METHYL-5-PYRIMIDYL)-3-PROPYL]-P-AMINOBENZOYL-L-GLUTAMIC ACID, A MERCAPTO ANALOG [J].

BAKER, BR ;

HO, BT ;

MORREAL, CE .

JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (06) :658-&

[3] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (04) :347-&

[4] ANALOGS OF TETRAHYDROFOLIC ACID .26. SYNTHESIS OF SOME 5-ARYL AND 5-ARALKYL PYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR EFFECT ON DIHYDROFOLIC REDUCTASE AND THYMIDYLATE SYNTHETASE [J].

BAKER, BR ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (02) :162-&

[5] ANALOGS OF TETRAHYDROFOLIC ACID .9. SYNTHESIS OF N-[1-(2-AMINO-4-HYDROXY-6-PHENYL-5-PYRIMIDYL)-3-PROPYL]-P-AMINOBENZOYL-L-GLUTAMIC ACID, A NONCLASSICAL INHIBITOR OF SOME FOLIC COFACTOR AREA ENZYMES [J].

BAKER, BR ;

SHAPIRO, HS .

JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (06) :664-&

[6] ANALOGS OF TETRAHYDROFOLOC ACID 34 - HYDROPHOBIC BONDING TO DIHYDROFOLOC REDUCTASE .6. MODE OF PHENYL BINDING OF SOME 6-ARYLPYRIMIDINES [J].

BAKER, BR ;

SHAPIRO, HS .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (03) :308-&

[7] ANALOGS OF TETRAHYDROFOLIC ACID .35. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE .7. SPECIES DIFFERENCES WITH SUBSTITUTED 4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES [J].

BAKER, BR ;

HO, BT .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (05) :470-&

[8] ANALOGS OF TETRAHYDROFOLIC ACID .25. 2,4-DIAMINO-6-PHENETHYLPTERIDINE AN INHIBITOR OF DIHYDROFOLIC REDUCTASE [J].

BAKER, BR ;

HO, BT .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (09) :1261-&

[9]

BAKER BR, 1966, J HETEROCYCLIC CHEM, V3, P319, DOI 10.1002/jhet.5570030316

[10] ANALOGS OF TETRAHYDROFOLIC ACID .21. SYNTHESIS OF 6-BROMOMETHYL-5-(P-CHLOROPHENYL)-2,4-DIAMINOPYRIMIDINE AND ITS EVALUATION AS A DIHYDROFOLIC REDUCTASE INHIBITOR [J].

BAKER, BR ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (01) :21-&

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