Substrain Differences, Gender, and Age of Spontaneously Hypertensive Rats Critically Determine Infarct Size Produced by Distal Middle Cerebral Artery Occlusion

被引：45

作者：

Hitonori Takaba ^{[1
]}

Kenji Fukuda ^{[2
]}

Hiroshi Yao ^{[3
]}

机构：

[1] St. Mary's Hospital,Department of Cerebrovascular Disease

[2] Hizen National Hospital,Laboratory for Neurochemistry

[3] Kyushu University,Department of Medicine and Clinical Science, Graduate School of Medical Sciences

来源：

Cellular and Molecular Neurobiology | 2004年 / 24卷 / 5期

关键词：

cerebral ischemia; focal; hypertension; photochemistry; genes; estrogens; aging;

D O I：

10.1023/B:CEMN.0000036400.55503.5e

中图分类号：

学科分类号：

摘要：

1. The present work discussed the effects of substrain or genetic differences, gender, and age of the rat on infarct size produced by distal middle cerebral artery occlusion (MCAO) in spontaneously hypertensive rats (SHR).

引用

页码：589 / 598

页数：9

共 202 条

[1]

Alkayed N. J.(2001)Estrogen and Bcl-2: Gene induction and effect of transgene in experimental stroke J. Neurosci. 21 7543-7550

[2]

Goto S.(1998)Gender-linked brain injury in experimental stroke Stroke 29 159-166

[3]

Sugo N.(2000)Neuroprotective effects of female gonadal steroids in reproductively senescent female rats Stroke 31 161-168

[4]

Joh H.-D.(1998)Photothrombotic middle cerebral artery occlusion in spontaneously hypertensive rats: Influence of substrain, gender and distal middle cerebral artery patterns on infarct size Stroke 29 1982-1987

[5]

Klaus J.(2002)Genetic aspects of stroke: Human and experimental studies J. Cereb. Blood Flow Metab 22 767-773

[6]

Crain B. J.(2002)Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats Am. J. Physiol. 278 H290-H294

[7]

Bernard O.(2002)Age-related decline of DNA repair activity for oxidative lesions in rat brain mitochondria J. Neurochem 81 1273-1284

[8]

Traystman R. J.(1983)Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) andWistar Kyoto (WKY) rats Stroke 14 605-611

[9]

Hurn P. D.(1984)Cerebral infarction after middle cerebral artery occlusion in progenies of spontaneously stroke-prone and normal rats Stroke 15 711-716

[10]

Alkayed N. J.(1995)Experimental stroke and neuroprotection in the aging rat brain Stroke 26 1072-1078

← 1 2 3 4 5 6 7 8 9 10 →