Detection of lung cancer using single-exposure dual-energy subtraction chest radiography

被引:32
作者
Ide K. [1 ,2 ]
Mogami H. [1 ,3 ]
Murakami T. [4 ]
Yasuhara Y. [5 ]
Miyagawa M. [6 ]
Mochizuki T. [4 ]
机构
[1] Department of Diagnostic and Therapeutic Radiology, Ehime University Postgraduate School of Medicine, Toon 791-0295
[2] Department of Radiology, Matsuyama Shimin Hospital, Matsuyama
[3] Department of Diagnostic and Therapeutic Radiology, Ehime University Postgraduate School of Medicine, Toon
[4] Department of Radiology, Ehime National Hospital, Toon
[5] Department of Radiology, Ehime Prefectural Central Hospital, Matsuyama
来源
Radiation Medicine | 2007年 / 25卷 / 5期
关键词
Chest radiography; Detectability; Lung cancer; Single-exposure dual-energy subtraction;
D O I
10.1007/s11604-007-0123-9
中图分类号
学科分类号
摘要
Purpose. The aim of this study was to evaluate the detectability of lung cancer by chest radiography with a single-exposure dual-energy subtraction (ES) method. Materials and methods. Five radiologists read two sets of chest radiographs from 77 patients (66.5 ± 9.6 years old) with histologically proven lung cancer measuring ≤3.0 cm and those from 77 normal subjects (65.7 ± 9.0 years old). The observer tests were performed in two sessions: standard computed radiography (CR) images only and a combination of CR and ES images. Receiver-operating characteristic analysis was used for statistical analysis. All tumors were classified into three groups according to the appearance on thin-section CT: (1) nonsolid: tumor shadow disappearance rate (TDR) was 100%; (2) partly solid: TDR was ≥50 but <100%; (3) solid: TDR was <50%. Results. Overall, detectability with the ES method was significantly better than that without ES (mean Az value increased from 0.7673 to 0.8265, P < 0.05). In the subgroup analysis of the nonsolid group and the solid group detectability did not change using the ES method, whereas in the partly solid group detectability with the ES method was significantly better than that without ES (mean Az value increased from 0.7162 to 0.8209, P < 0.005). Conclusion. The ES method improves the detectability of lung cancer by chest radiography, especially of the partly solid group. © 2007 Japan Radiological Society.
引用
收藏
页码:195 / 201
页数:6
相关论文
共 27 条
[1]  
Kaneko M., Eguchi K., Ohmatsu H., Kakinuma R., Naruke T., Suemasu K., Et al., Peripheral lung cancer: Screening and detection with low-dose spiral CT versus radiography, Radiology, 201, pp. 798-802, (1996)
[2]  
Henschke C.I., McCauley D.I., Yankelevitz D.F., Naidich D.P., McGuinness G., Miettinen O.S., Et al., Early Lung Cancer Action Project: Overall design and findings from baseline screening, Lancet, 354, pp. 99-105, (1999)
[3]  
Quekel L.G., Kessels A.G., Goei R., Van Engelshoven J.M., Miss rate of lung cancer on the chest radiograph in clinical practice, Chest, 115, pp. 720-4, (1999)
[4]  
Ho J.T., Kruger R.A., Comparison of dual-energy and conventional chest radiography for nodule detection, Invest Radiol, 24, pp. 861-8, (1989)
[5]  
Kelcz F., Zink F.E., Peppler W.W., Kruger D.G., Ergun D.L., Mistretta C.A., Conventional chest radiography vs dual-energy computed radiography in the detection and characterization of pulmonary nodules, AJR Am J Roentgenol, 162, pp. 271-8, (1994)
[6]  
Takashima T., Single exposure energy subtraction chest radiography in the diagnosis of pulmonary cancer, Nippon Igaku Hoshasen Gakkai Zasshi, 47, pp. 455-64, (1987)
[7]  
Niklason L.T., Hickey N.M., Chakraborty D.P., Sabbagh E.A., Yester M.V., Fraser R.G., Et al., Simulated pulmonary nodules: Detection with dual-energy digital versus conventional radiography, Radiology, 160, pp. 589-93, (1986)
[8]  
Takamochi K., Nagai K., Yoshida J., Suzuki K., Ohde Y., Nishimura M., Et al., Pathologic N0 status in pulmonary adenocarcinoma is predictable by combining serum carcinoembryonic antigen level and computed tomographic findings, J Thorac Cardiovasc Surg, 122, pp. 325-30, (2001)
[9]  
Asamura H., Suzuki K., Watanabe S., Matsuno Y., Maeshima A., Tsuchiya R., A clinicopathological study of resected subcentimeter lung cancers: A favorable prognosis for ground glass opacity lesions, Ann Thorac Surg, 76, pp. 1016-22, (2003)
[10]  
Dorfman D.D., Berbaum K.S., Metz C.E., Receiver operating characteristic rating analysis: Generalization to the population of readers and patients with the jackknife method, Invest Radiol, 27, pp. 723-31, (1992)