Potent and selective mechanism-based inhibition of gelatinases

被引:186
作者
Brown, S
Bernardo, MM
Li, ZH
Kotra, LP
Tanaka, Y
Fridman, R
Mobashery, S [1 ]
机构
[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA
[2] Wayne State Univ, Dept Pathol, Detroit, MI 48202 USA
关键词
D O I
10.1021/ja001461n
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:6799 / 6800
页数:2
相关论文
共 23 条
[1]   Recent advances in matrix metalloproteinase inhibitor research [J].
Beckett, RP ;
Davidson, AH ;
Drummond, AH ;
Huxley, P ;
Whittaker, M .
DRUG DISCOVERY TODAY, 1996, 1 (01) :16-26
[2]   Tissue inhibitors of metalloproteinases: evolution, structure and function [J].
Brew, K ;
Dinakarpandian, D ;
Nagase, H .
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 2000, 1477 (1-2) :267-283
[3]   Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression:: Correlation with invasive growth of breast cancer [J].
Dalberg, K ;
Eriksson, E ;
Enberg, U ;
Kjellman, M ;
Bäckdahl, M .
WORLD JOURNAL OF SURGERY, 2000, 24 (03) :334-340
[4]  
Dumas V, 1999, ANTICANCER RES, V19, P2929
[5]  
Forget MA, 1999, CAN J PHYSIOL PHARM, V77, P465
[6]   Discovery of a novel series of selective MMP inhibitors:: Identification of the γ-sulfone-thiols [J].
Freskos, JN ;
Mischke, BV ;
DeCrescenzo, GA ;
Heintz, R ;
Getman, DP ;
Howard, SC ;
Kishore, NN ;
McDonald, JJ ;
Munie, GE ;
Rangwala, S ;
Swearingen, CA ;
Voliva, C ;
Welsch, DJ .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (07) :943-948
[7]   Thirty-six years in the clinic without an MMP inhibitor - What hath collagenase wrought? [J].
Greenwald, RA .
INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC APPLICATIONS, 1999, 878 :413-419
[8]   Structural insights into the catalytic domains of human matrix metalloprotease-2 and human matrix metalloprotease-9: Implications for substrate specificities [J].
Massova, I ;
Fridman, R ;
Mobashery, S .
JOURNAL OF MOLECULAR MODELING, 1997, 3 (01) :17-30
[9]   Matrix metalloproteinases: structures, evolution, and diversification [J].
Massova, I ;
Kotra, LP ;
Fridman, R ;
Mobashery, S .
FASEB JOURNAL, 1998, 12 (12) :1075-1095
[10]  
Michaelides MR, 1999, CURR PHARM DESIGN, V5, P787