Seroprevalence of human metapneumovirus in Japan

被引:122
作者
Ebihara, T [1 ]
Endo, R [1 ]
Kikuta, H [1 ]
Ishiguro, N [1 ]
Yoshioka, M [1 ]
Ma, XM [1 ]
Kobayashi, K [1 ]
机构
[1] Hokkaido Univ, Dept Pediat, Sch Med, Kita Ku, Sapporo, Hokkaido 0608638, Japan
关键词
human metapneumovirus; human respiratory syncytial virus; indirect immunofluorescence assay;
D O I
10.1002/jmv.10391
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A new human pneumovirus, provisionally designated human metapneumovirus, was discovered by Dutch researchers. We examined 142 serum samples from the general population aged from 1 month to 35 years in Japan for human metapneumovirus antibody by indirect immunofluorescence assays using human metapneumovirus-infected monkey kidney cells. The overall prevalence of human metapneumovirus infection was 72.5%. The seropositive rate was lowest in the age group of 6 months to 1 year and gradually increased with age. All of the children had been exposed to human metapneumovirus by the age of 10 years. The results show that human metapneumovirus is circulating in the Japanese population and is a ubiquitous virus acquired early in life.
引用
收藏
页码:281 / 283
页数:3
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