FlyBase: genes and gene models

被引:272
作者
Drysdale, RA
Crosby, MA
机构
[1] Harvard Univ, Biol Labs, Cambridge, MA 02138 USA
[2] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England
[3] Harvard Univ, Biol Labs, Cambridge, MA 02138 USA
[4] Univ Cambridge, Cambridge CB2 1TN, England
[5] Indiana Univ, Dept Biol, Bloomington, IN USA
[6] Univ Calif Berkeley, Berkeley, CA 94720 USA
[7] Lawrence Berkeley Lab, Berkeley, CA USA
基金
美国国家卫生研究院; 英国医学研究理事会;
关键词
D O I
10.1093/nar/gki046
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
FlyBase (http://flybase.org) is the primary repository of genetic and molecular data of the insect family Drosophilidae. For the most extensively studied species, Drosophila melanogaster, a wide range of data are presented in integrated formats. Data types include mutant phenotypes, molecular characterization of mutant alleles and aberrations, cytological maps, wild-type expression patterns, anatomical images, transgenic constructs and insertions, sequence-level gene models and molecular classification of gene product functions. There is a growing body of data for other Drosophila species; this is expected to increase dramatically over the next year, with the completion of draft-quality genomic sequences of an additional 11 Drosphila species.
引用
收藏
页码:D390 / D395
页数:6
相关论文
共 19 条
[1]   The genome sequence of Drosophila melanogaster [J].
Adams, MD ;
Celniker, SE ;
Holt, RA ;
Evans, CA ;
Gocayne, JD ;
Amanatides, PG ;
Scherer, SE ;
Li, PW ;
Hoskins, RA ;
Galle, RF ;
George, RA ;
Lewis, SE ;
Richards, S ;
Ashburner, M ;
Henderson, SN ;
Sutton, GG ;
Wortman, JR ;
Yandell, MD ;
Zhang, Q ;
Chen, LX ;
Brandon, RC ;
Rogers, YHC ;
Blazej, RG ;
Champe, M ;
Pfeiffer, BD ;
Wan, KH ;
Doyle, C ;
Baxter, EG ;
Helt, G ;
Nelson, CR ;
Miklos, GLG ;
Abril, JF ;
Agbayani, A ;
An, HJ ;
Andrews-Pfannkoch, C ;
Baldwin, D ;
Ballew, RM ;
Basu, A ;
Baxendale, J ;
Bayraktaroglu, L ;
Beasley, EM ;
Beeson, KY ;
Benos, PV ;
Berman, BP ;
Bhandari, D ;
Bolshakov, S ;
Borkova, D ;
Botchan, MR ;
Bouck, J ;
Brokstein, P .
SCIENCE, 2000, 287 (5461) :2185-2195
[2]  
Apweiler R, 2004, NUCLEIC ACIDS RES, V32, pD115, DOI [10.1093/nar/gkw1099, 10.1093/nar/gkh131]
[3]   Gene expression during the life cycle of Drosophila melanogaster [J].
Arbeitman, MN ;
Furlong, EEM ;
Imam, F ;
Johnson, E ;
Null, BH ;
Baker, BS ;
Krasnow, MA ;
Scott, MP ;
Davis, RW ;
White, KP .
SCIENCE, 2002, 297 (5590) :2270-2275
[4]   The GRID: The General Repository for Interaction Datasets [J].
Breitkreutz, BJ ;
Stark, C ;
Tyers, M .
GENOME BIOLOGY, 2003, 4 (03)
[5]   The Interactive Fly: gene networks, development and the Internet [J].
Brody, T .
TRENDS IN GENETICS, 1999, 15 (08) :333-334
[6]  
CELNIKER SE, 2002, GENOME BIOL, V3, pR79
[7]   Functional proteomics mapping of a human signaling pathway [J].
Colland, F ;
Jacq, X ;
Trouplin, V ;
Mougin, C ;
Groizeleau, C ;
Hamburger, A ;
Meil, A ;
Wojcik, J ;
Legrain, P ;
Gauthier, JM .
GENOME RESEARCH, 2004, 14 (07) :1324-1332
[8]  
Drysdale R, 2001, Brief Bioinform, V2, P68, DOI 10.1093/bib/2.1.68
[9]   Gene Expression Omnibus: NCBI gene expression and hybridization array data repository [J].
Edgar, R ;
Domrachev, M ;
Lash, AE .
NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :207-210
[10]   The FlyBase database of the Drosophila genome projects and community literature [J].
Gelbart, W ;
Bayraktaroglu, L ;
Bettencourt, B ;
Campbell, K ;
Crosby, M ;
Emmert, D ;
Hradecky, P ;
Huang, Y ;
Letovsky, S ;
Matthews, B ;
Russo, S ;
Schroeder, A ;
Smutniak, F ;
Zhou, P ;
Zytkovicz, M ;
Ashburner, M ;
Drysdale, R ;
de Grey, A ;
Foulger, R ;
Millburn, G ;
Yamada, C ;
Kaufman, T ;
Matthews, K ;
Gilbert, D ;
Grumbling, G ;
Strelets, V ;
Shemen, C ;
Rubin, G ;
Berman, B ;
Frise, E ;
Gibson, M ;
Harris, N ;
Kaminker, J ;
Lewis, S ;
Marshall, B ;
Misra, S ;
Mungall, C ;
Prochnik, S ;
Richter, J ;
Smith, C ;
Shu, S ;
Tupy, J ;
Wiel, C .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :172-175