Mechanisms of disease:: Sodium and potassium in the pathogenesis of hypertension

被引：524

作者：

Adrogue, Horacio J.

Madias, Nicolaos E.

机构：

[1] Caritas St Elizabeths Med Ctr, Dept Med, Div Nephrol, Boston, MA 02135 USA

[2] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[3] Baylor Univ, Methodist Hosp, Dept Med, Houston, TX 77030 USA

[4] Vet Affairs Med Ctr, Houston, TX 77030 USA

[5] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2007年 / 356卷 / 19期

关键词：

D O I：

10.1056/NEJMra064486

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This review examines epidemiologic, physiological, and molecular evidence that the interplay between sodium and potassium is central to the development of hypertension. The review concludes with recommendations for reducing sodium and increasing potassium in the diet. Copyright © 2007 Massachusetts Medical Society.

引用

收藏

页码：1966 / 1978

页数：13

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