Thromboelastography identifies sex-related differences in coagulation

被引:116
作者
Gorton, HJ [1 ]
Warren, ER [1 ]
Simpson, NAB [1 ]
Lyons, GR [1 ]
Columb, MO [1 ]
机构
[1] St Jamess Univ Hosp, Dept Anesthesia, Leeds, W Yorkshire, England
关键词
D O I
10.1097/00000539-200011000-00042
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Thromboelastography is an in vitro, point-of-care monitor of whole blood coagulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to female sex hormones. The aim of the study was to determine if sex, in addition to pregnancy, affected thromboelastography variables by studying male and female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P<0.01) differences in sex, with a significant (P<0.0001) trend of increasing whole blood coagulability from men through nonpregnant to pregnant women. The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.
引用
收藏
页码:1279 / 1281
页数:3
相关论文
共 6 条
[1]  
Department of Health, 1996, REP CONF ENQ MAT DEA
[2]  
FISCH IR, 1972, CLIN PHARMACOL THER, V14, P238
[3]  
HAWTHORNE L, 1997, CLIN PROBLEMS OBSTET, P67
[4]   Epidemiology of coagulation factors, inhibitors and activation markers: The Third Glasgow MONICA Survey .1. Illustrative reference ranges by age, sex and hormone use [J].
Lowe, GDO ;
Rumley, A ;
Woodward, M ;
Morrison, CE ;
Philippou, H ;
Lane, DA ;
TunstallPedoe, H .
BRITISH JOURNAL OF HAEMATOLOGY, 1997, 97 (04) :775-784
[5]  
Rosendaal FR, 1997, THROMB HAEMOSTASIS, V78, P1
[6]   Thromboelastographic changes in healthy parturients and postpartum women [J].
Sharma, SK ;
Philip, J ;
Wiley, J .
ANESTHESIA AND ANALGESIA, 1997, 85 (01) :94-98