Cadherins in embryonic and neural morphogenesis

被引：384

作者：

Tepass, U

Truong, K

Godt, D

Ikura, M

Peifer, M

机构：

[1] Univ Toronto, Dept Zool, Toronto, ON M5S 3G5, Canada

[2] Ontario Canc Inst, Div Mol & Struct Biol, Toronto, ON M5G 2M9, Canada

[3] Univ Toronto, Dept Med Biophys, Toronto, ON M5G 2M9, Canada

[4] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2000年 / 1卷 / 02期

关键词：

D O I：

10.1038/35040042

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cadherins not only maintain the structural integrity of cells and tissues but also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also contribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.

引用

收藏

页码：91 / 100

页数：10

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