A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a

被引：9

作者：

Eskdale, J

Turestkaya, RL

Armstrong, C

Kuprash, DV

Nedospasov, SA

Gallagher, G

机构：

[1] Univ Glasgow, Royal Infirm, Dept Surg, Glasgow G31 2ER, Lanark, Scotland

[2] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Lab Mol Immunol, Moscow 117984, Russia

[3] Moscow MV Lomonosov State Univ, Belozersky Inst Physicochem Biol, Moscow 119899, Russia

[4] SAIC Frederick, Intramural Res Support Program, Frederick, MD 21702 USA

[5] NCI, Mol Immunoregulat Lab, Div Basic Sci, Frederick Canc Res & Dev Ctr, Frederick, MD 21702 USA

来源：

GENES AND IMMUNITY | 2000年 / 1卷 / 03期

关键词：

microsatellite; TNF; TNF-R1; CD1ZOa; polymorphism;

D O I：

10.1038/sj.gene.6363663

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We provide characterization of a highly polymorphic dinucleotide repeat in the human TNF-receptor 1 gene (TNFR1, TNFRp55, CD120a). We have observed 11 alleles at this locus in individuals from the West of Scotland. in a panel of healthy, unrelated individuals from the West of Scotland (n = 143), the overall heterozygosity was 68%, indicating the potential usefulness of these markers in immunogenetic studies.

引用

页码：228 / 230

页数：3

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