Towards an e-biology of ageing: integrating theory and data

被引：65

作者：

Kirkwood, TBL ^{[1
]}

Boys, RJ

Gillespie, CS

Proctor, CJ

Shanley, DP

Wilkinson, DJ

机构：

[1] Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England

[2] Newcastle Univ, Sch Math & Stat, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 03期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nrm1051

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Ageing is a highly complex process; it involves interactions between numerous biochemical and cellular mechanisms that affect many tissues in an organism. Although work on the biology of ageing is now advancing quickly, this inherent complexity means that information remains highly fragmented. We describe how a new web-based modelling initiative is seeking to integrate data and hypotheses from diverse biological sources.

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收藏

页码：243 / 249

页数：7

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