Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity

被引：437

作者：

Grabbe, S ^{[1
]}

Schwarz, T ^{[1
]}

机构：

[1] Univ Munster, Dept Dermatol, D-48149 Munster, Germany

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 01期

关键词：

D O I：

10.1016/S0167-5699(97)01186-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Although the pathophysiology of contact hypersensitivity (CHS) might appear to be well understood, this only applies to the sensitization phase. Little is known about the elicitation phase, and fundamental differences exist between CHS and other forms of delayed-type hypersensitivity responses. Here, Stephan Grabbe and Thomas Schwarz summarize the role of different cellular components and soluble mediators in the inflammatory tissue response during CHS elicitation.

引用

收藏

页码：37 / 44

页数：8

相关论文

共 100 条

[1] Cytokine gene expression during the elicitation phase of contact sensitivity: Regulation by endogenous IL-4 [J].

Asada, H ;

Linton, J ;

Katz, SI .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1997, 108 (04) :406-411

[2]

ASAHINA A, 1995, J IMMUNOL, V154, P3056

[3]

ASKENASE PW, 1995, J IMMUNOL, V154, P3644

[4] P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues [J].

Austrup, F ;

Vestweber, D ;

Borges, E ;

Lohning, M ;

Brauer, R ;

Herz, U ;

Renz, H ;

Hallmann, R ;

Scheffold, A ;

Radbruch, A ;

Hamann, A .

NATURE, 1997, 385 (6611) :81-83

[5] CTLA4IG PROLONGS ALLOGRAFT SURVIVAL WHILE SUPPRESSING CELL-MEDIATED-IMMUNITY [J].

BALIGA, P ;

CHAVIN, KD ;

QIN, LH ;

WOODWARD, J ;

LIN, JX ;

LINSLEY, PS ;

BROMBERG, JS .

TRANSPLANTATION, 1994, 58 (10) :1082-1090

[6] KERATINOCYTES AS INITIATORS OF INFLAMMATION [J].

BARKER, JNWN ;

MITRA, RS ;

GRIFFITHS, CEM ;

DIXIT, VM ;

NICKOLOFF, BJ .

LANCET, 1991, 337 (8735) :211-214

[7]

Becker D, 1993, Exp Dermatol, V2, P63, DOI 10.1111/j.1600-0625.1993.tb00010.x

[8] INTERLEUKIN-10 BUT NOT INTERLEUKIN-4 IS A NATURAL SUPPRESSANT OF CUTANEOUS INFLAMMATORY RESPONSES [J].

BERG, DJ ;

LEACH, MW ;

KUHN, R ;

RAJEWSKY, K ;

MULLER, W ;

DAVIDSON, NJ ;

RENNICK, D .

JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (01) :99-108

[9] An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction [J].

Bernhagen, J ;

Bacher, M ;

Calandra, T ;

Metz, CN ;

Doty, SB ;

Donnelly, T ;

Bucala, R .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (01) :277-282

[10] THE SKIN IMMUNE-SYSTEM - PROGRESS IN CUTANEOUS BIOLOGY [J].

BOS, JD ;

KAPSENBERG, ML .

IMMUNOLOGY TODAY, 1993, 14 (02) :75-78

← 1 2 3 4 5 6 7 8 9 10 →