The complement system as a therapeutic target in autoimmunity

被引：80

作者：

Holers, VM ^{[1
]}

机构：

[1] Univ Colorado, Hlth Sci Ctr, Dept Med & Immunol, Denver, CO 80262 USA

来源：

CLINICAL IMMUNOLOGY | 2003年 / 107卷 / 03期

关键词：

C5A RECEPTOR ANTAGONIST; INNATE IMMUNE-SYSTEM; C-REACTIVE PROTEIN; C3A ANAPHYLATOXIN RECEPTOR; COLLAGEN-INDUCED ARTHRITIS; ISCHEMIA-REPERFUSION; MONOCLONAL-ANTIBODY; INFLAMMATORY MEDIATORS; NATURAL ANTIBODY; MICE DEFICIENT;

D O I：

10.1016/S1521-6616(03)00034-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：140 / 151

页数：12

共 162 条

[1] STRUCTURE AND FUNCTION OF THE COMPLEMENT RECEPTORS, CR-1 (CD35) AND CR-2 (CD21) [J].

AHEARN, JM ;

FEARON, DT .

ADVANCES IN IMMUNOLOGY, 1989, 46 :183-219

[2] Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen [J].

Ahearn, JM ;

Fischer, MB ;

Croix, D ;

Goerg, S ;

Ma, MH ;

Xia, JR ;

Zhou, XN ;

Howard, RG ;

Rothstein, TL ;

Carroll, MC .

IMMUNITY, 1996, 4 (03) :251-262

[3] Molecular cloning and characterization of the human anaphylatoxin C3a receptor [J].

Ames, RS ;

Li, Y ;

Sarau, HM ;

Nuthulaganti, P ;

Foley, JJ ;

Ellis, C ;

Zeng, ZZ ;

Su, K ;

Jurewicz, AJ ;

Hertzberg, RP ;

Bergsma, DJ ;

Kumar, C .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (34) :20231-20234

[4] Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models [J].

Ames, RS ;

Lee, D ;

Foley, JJ ;

Jurewicz, AJ ;

Tornetta, MA ;

Bautsch, W ;

Settmacher, B ;

Klos, A ;

Erhard, KF ;

Cousins, RD ;

Sulpizio, AC ;

Hieble, JP ;

McCafferty, G ;

Ward, KW ;

Adams, JL ;

Bondinell, WE ;

Underwood, DC ;

Osborn, RR ;

Badger, AM ;

Sarau, HM .

JOURNAL OF IMMUNOLOGY, 2001, 166 (10) :6341-6348

[5]

AUBRY JP, 1994, J IMMUNOL, V152, P5806

[6] CD21 IS A LIGAND FOR CD23 AND REGULATES IGE PRODUCTION [J].

AUBRY, JP ;

POCHON, S ;

GRABER, P ;

JANSEN, KU ;

BONNEFOY, JY .

NATURE, 1992, 358 (6386) :505-507

[7]

BAO L, 2003, IN PRESS J AM SOC NE

[8] Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice [J].

Bao, LH ;

Haas, M ;

Boackle, SA ;

Kraus, DM ;

Cunningham, PN ;

Park, P ;

Alexander, JJ ;

Anderson, RK ;

Culhane, K ;

Holers, VM ;

Quigg, RJ .

JOURNAL OF IMMUNOLOGY, 2002, 168 (07) :3601-3607

[9] COMPLEMENT LYTIC ACTIVITY HAS NO ROLE IN THE PATHOGENESIS OF AUTOIMMUNE DIABETES IN NOD MICE [J].

BAXTER, AG ;

COOKE, A .

DIABETES, 1993, 42 (11) :1574-1578

[10] The major receptor for C-reactive protein on leukocytes is Fcγ receptor II [J].

Bharadwaj, D ;

Stein, MP ;

Volzer, M ;

Mold, C ;

Du Clos, TW .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (04) :585-590

← 1 2 3 4 5 6 7 8 9 10 →