Signaling angiogenesis and lymphangiogenesis

被引：160

作者：

Korpelainen, EI ^{[1
]}

Alitalo, K ^{[1
]}

机构：

[1] Univ Helsinki, Haartman Inst, Mol Canc Biol Lab, FIN-00014 Helsinki, Finland

来源：

CURRENT OPINION IN CELL BIOLOGY | 1998年 / 10卷 / 02期

关键词：

D O I：

10.1016/S0955-0674(98)80137-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Exciting progress has been made in elucidating the complex network of receptor-ligand interactions that regulate blood vessel growth. Understanding these control mechanisms is of interest not only because of their role in developmental biology, but because they provide potential therapeutic strategies for disease processes involving angiogenesis, such as tumor growth. (C) Current Biology Ltd ISSN 0955-0674.

引用

页码：159 / 164

页数：6

共 59 条

[1] Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4) [J].

Achen, MG ;

Jeltsch, M ;

Kukk, E ;

Mäkinen, T ;

Vitali, A ;

Wilks, AF ;

Alitalo, K ;

Stacker, SA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (02) :548-553

[2] SUPPRESSION OF RETINAL NEOVASCULARIZATION IN-VIVO BY INHIBITION OF VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) USING SOLUBLE VEGF-RECEPTOR CHIMERIC PROTEINS [J].

AIELLO, LP ;

PIERCE, EA ;

FOLEY, ED ;

TAKAGI, H ;

CHEN, H ;

RIDDLE, L ;

FERRARA, N ;

KING, GL ;

SMITH, LEH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (23) :10457-10461

[3] VASCULAR ENDOTHELIAL GROWTH-FACTOR ACTS AS A SURVIVAL FACTOR FOR NEWLY FORMED RETINAL-VESSELS AND HAS IMPLICATIONS FOR RETINOPATHY OF PREMATURITY [J].

ALON, T ;

HEMO, I ;

ITIN, A ;

PEER, J ;

STONE, J ;

KESHET, E .

NATURE MEDICINE, 1995, 1 (10) :1024-1028

[4] Isolation of putative progenitor endothelial cells for angiogenesis [J].

Asahara, T ;

Murohara, T ;

Sullivan, A ;

Silver, M ;

vanderZee, R ;

Li, T ;

Witzenbichler, B ;

Schatteman, G ;

Isner, JM .

SCIENCE, 1997, 275 (5302) :964-967

[5] Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal [J].

Benjamin, LE ;

Keshet, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (16) :8761-8766

[6] INTEGRIN ALPHA(V)BETA(3) ANTAGONISTS PROMOTE TUMOR-REGRESSION BY INDUCING APOPTOSIS OF ANGIOGENIC BLOOD-VESSELS [J].

BROOKS, PC ;

MONTGOMERY, AMP ;

ROSENFELD, M ;

REISFELD, RA ;

HU, TH ;

KLIER, G ;

CHERESH, DA .

CELL, 1994, 79 (07) :1157-1164

[7] Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3 [J].

Brooks, PC ;

Stromblad, S ;

Sanders, LC ;

vonSchalscha, TL ;

Aimes, RT ;

StetlerStevenson, WG ;

Quigley, JP ;

Cheresh, DA .

CELL, 1996, 85 (05) :683-693

[8] Heterodimers of placenta growth factor vascular endothelial growth factor - Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR [J].

Cao, YH ;

Chen, H ;

Zhou, L ;

Chiang, MK ;

AnandApte, B ;

Weatherbee, JA ;

Wang, YD ;

Fang, FY ;

Flanagan, JG ;

Tsang, MLS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (06) :3154-3162

[9] Role of tissue factor in embryonic blood vessel development [J].

Carmeliet, P ;

Mackman, N ;

Moons, L ;

Luther, T ;

Gressens, P ;

VanVlaenderen, I ;

Demunck, H ;

Kasper, M ;

Breier, G ;

Evrard, P ;

Muller, M ;

Risau, W ;

Edgington, T ;

Collen, D .

NATURE, 1996, 383 (6595) :73-75

[10] Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele [J].

Carmeliet, P ;

Ferreira, V ;

Breier, G ;

Pollefeyt, S ;

Kieckens, L ;

Gertsenstein, M ;

Fahrig, M ;

Vandenhoeck, A ;

Harpal, K ;

Eberhardt, C ;

Declercq, C ;

Pawling, J ;

Moons, L ;

Collen, D ;

Risau, W ;

Nagy, A .

NATURE, 1996, 380 (6573) :435-439

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