Effect of simvastatin on ischemic signs and symptoms in the Scandinavian Simvastatin Survival Study (4S)

被引：327

作者：

Pedersen, TR ^{[1
]}

Kjekshus, J

Pyörälä, K

Olsson, AG

Cook, TJ

Musliner, TA

Tobert, JA

Haghfelt, T

机构：

[1] Univ Oslo, Aker Hosp, Med Clin, Dept Cardiol, N-0514 Oslo, Norway

[2] Univ Oslo, Natl Hosp, Oslo, Norway

[3] Kuopio Univ Hosp, SF-70210 Kuopio, Finland

[4] Fac Hlth Sci, Linkoping, Sweden

[5] Merck Res Labs, Rahway, NJ USA

[6] Odense Univ Hosp, DK-5000 Odense, Denmark

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 81卷 / 03期

关键词：

D O I：

10.1016/S0002-9149(97)00904-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In patients participating in the Scandinavian Simvastatin Survival Study, cholesterol lowering with simvastatin reduced the incidence of carotid bruits and cerebrovascular events as well as new-onset or worsening of angina pectoris and intermittent claudication. These effects suggest that simvastatin may have a general antiatherosclerotic effect not limited to the coronary bed.

引用

页码：333 / 335

页数：3

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