Imaging transgenic animals

被引：78

作者：

Budinger, TF ^{[1
]}

Benaron, DA

Koretsky, AP

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Dept Bioengn, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Ctr Funct Imaging, Berkeley, CA 94720 USA

[3] Stanford Univ, Dept Phys, HEPL, Stanford, CA 94305 USA

[4] Carnegie Mellon Univ, Dept Biol Sci, Pittsburgh, PA 15213 USA

来源：

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING | 1999年 / 1卷

关键词：

transgenic; emission imaging; positron emission tomography; single photon tomography; magnetic resonance imaging; optical imaging; magnetic resonance spectroscopy; gene expression;

D O I：

10.1146/annurev.bioeng.1.1.611

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Transgenic and eugenic animals as small as 30 g can be studied noninvasively by radionuclides with resolutions of 1-2 mm, by MRT with resolution of 100 mu m and by light fluorescence and bioluminescence with high sensitivities. The technologies of radionuclide emission, magnetic resonance imaging, magnetic resonance spectroscopy, optical tomography, optical fluorescence and optical bioluminescence are currently being applied to small-animal studies. These technologies and examples of their applications are reviewed in this chapter.

引用

页码：611 / 648

页数：44

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