Developmental biology - Control by combinatorial codes

被引：23

作者：

Ghazi, A ^{[1
]}

VijayRaghavan, K ^{[1
]}

机构：

[1] Tata Inst Fundamental Res, Natl Ctr Biol Sci, Bangalore 560065, Karnataka, India

来源：

NATURE | 2000年 / 408卷 / 6811期

关键词：

D O I：

10.1038/35044174

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Studies in fruitflies support the idea that regulatory regions of genes control development by acting as molecular 'computers', calculating cell fate according to the combined effects of several signalling pathways.

引用

页码：419 / 420

页数：2

共 5 条

[1] Combinatorial signaling codes for the progressive determination of cell fates in the Drosophila embryonic mesoderm [J].

Carmena, A ;

Gisselbrecht, S ;

Harrison, J ;

Jiménez, F ;

Michelson, AM .

GENES & DEVELOPMENT, 1998, 12 (24) :3910-3922

[2] Combinatorial signaling in the specification of unique cell fates [J].

Flores, GV ;

Duan, H ;

Yan, HJ ;

Nagaraj, R ;

Fu, WM ;

Zou, Y ;

Noll, M ;

Banerjee, U .

CELL, 2000, 103 (01) :75-85

[3] Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors [J].

Halfon, MS ;

Carmena, A ;

Gisselbrecht, S ;

Sackerson, CM ;

Jiménez, F ;

Baylies, MK ;

Michelson, AM .

CELL, 2000, 103 (01) :63-74

[4] Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye [J].

Xu, CY ;

Kauffmann, RC ;

Zhang, JJ ;

Kladny, S ;

Carthew, RW .

CELL, 2000, 103 (01) :87-97

[5] Genomic cis-regulatory logic: Experimental and computational analysis of a sea urchin gene [J].

Yuh, CH ;

Bolouri, H ;

Davidson, EH .

SCIENCE, 1998, 279 (5358) :1896-1902

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