Deleterious nutations and the evolution of sex

被引：177

作者：

Keightley, PD

Eyre-Walker, A

机构：

[1] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland

[2] Univ Sussex, Ctr Study Evolut, Brighton BN1 9QG, E Sussex, England

[3] Univ Sussex, Sch Biol Sci, Brighton BN1 9QG, E Sussex, England

来源：

SCIENCE | 2000年 / 290卷 / 5490期

关键词：

D O I：

10.1126/science.290.5490.331

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

It has been suggested that sexual reproduction is maintained because it reduces the load imposed by recurrent deleterious mutations. If rates of deleterious mutation per diploid genome per generation (U) exceed 1, and mutations interact synergistically, then sexuals can overcome their inherent twofold disadvantage. We have tested this hypothesis by estimating genomic point mutation rates for protein-coding genes in a range of animal taxa. We find a positive Linear relationship between U and generation time. In species with short generation times. U is predicted to be far below 1, suggesting that sex is not maintained by its capacity to purge the genome of deleterious mutations.

引用

页码：331 / 333

页数：3

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