Microarc oxidation coating covered Ti implants with micro-scale gouges formed by a multi-step treatment for improving osseointegration

被引：22

作者：

Bai, Yixin ^{[1
]}

Zhou, Rui ^{[2
,3
]}

Cao, Jianyun ^{[4
]}

Wei, Daqing ^{[3
]}

Du, Qing ^{[3
]}

Li, Baoqiang ^{[3
]}

Wang, Yarning ^{[3
]}

Jia, Dechang ^{[3
]}

Zhou, Yu ^{[3
]}

机构：

[1] Harbin Med Univ, Dept Dent Med, Harbin 150081, Peoples R China

[2] Xi An Jiao Tong Univ, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China

[3] Harbin Inst Technol, Dept Mat Sci & Engn, Harbin 150001, Peoples R China

[4] Univ Manchester, Sch Mat, Oxford Rd, Manchester M13 9PL, Lancs, England

来源：

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2017年 / 76卷

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Titanium; Microarc oxidation; Micro-scale gouges; -OH functional group; Osseointegration; TITANIUM SURFACE; BONE INGROWTH; NA; SI; OSTEOCONDUCTIVITY; ABILITY; MATRIX; CA;

D O I：

10.1016/j.msec.2017.03.071

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

082905 [生物质能源与材料]; 100103 [病原生物学];

摘要：

The sub-microporous microarc oxidation (MAO) coating covered Ti implant with micro-scale gouges has been fabricated via a multi-step MAO process to overcome the compromised bone-implant integration. The as prepared implant has been further mediated by post-heat treatment to compare the effects of -OH functional group and the nano-scale orange peel-like morphology on osseointegration. The bone regeneration, bone implant contact interface, and biomechanical push-out force of the modified Ti implant have been discussed thoroughly in this work. The greatly improved push-out force for the MAO coated Ti implants with micro-scale gouges could be attributed to the excellent mechanical interlocking effect between implants and biologically meshed bone tissues. Attributed to the -OH functional group which promotes synostosis between the biologically meshed bone and the gouge surface of implant, the multi-step MAO process could be an effective strategy to improve the osseointegration of Ti implant. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：908 / 917

页数：10

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