Chemical properties of sperm whale myoglobins reconstituted with monopropionate hemins

被引：7

作者：

Hayashi, T ^{[1
]}

Nakagawa, T

Harada, K

Matsuo, T

Hitomi, Y

Hisaeda, Y

机构：

[1] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Fukuoka 8128581, Japan

[2] Kyoto Univ, Grad Sch Engn, Dept Mol Engn, Kyoto 6158510, Japan

来源：

CHEMISTRY LETTERS | 2004年 / 33卷 / 11期

关键词：

D O I：

10.1246/cl.2004.1512

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The binding behavior of two heme-propionate side chains in sperm whale myoglobin was evaluated using artificially created hemins, 6-methyl-7-propionate- and 6-propionate-7-methyl-protohemin IX. From the thermodynamic study of the hemin binding to apomyoglobin, it was found that two heme-propionates clearly contribute to the stabilization of the hemin in the protein matrix.

引用

页码：1512 / 1513

页数：2

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